Document Detail


TO5 as a magnetization transfer contrast test object: characterization of the gels and determination of the real magnetization transfer.
MedLine Citation:
PMID:  9220408     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Following the work of the European concerted action, "Tissue characterization by magnetic resonance spectroscopy and imaging," sets of five test objects (TO) were designed, produced, and distributed among European laboratories. The TO were designed to control the image quality of clincial magnetic resonance imaging in an independent and uniform mode. The fifth test object (TO5) was devoted to relaxation measurements and composed of 18 agarose tubes, inserted in an holder filled with a CuSO4 solution. These gels are subject to magnetization transfer (MT). The purpose of this paper is to characterize their MT parameters. An individual study of each gel was performed in a spectrometer, and an individual fit, as well as a global fit, was done on the two-pool model. The MT parameters found in each case are in agreement with the known properties of the agarose gels and given below. The real MT (transfer of magnetization from water to macromolecules) was computed, taking into account the "bleeding over" (direct saturation of the water magnetization). The maximum real MT ranges from 15 to 35% and can be obtained with almost the same saturation pulse conditions for all the gels. However, the saturating field required to reach the maximum MT is very high (46 microT) and unserviceable on a clinical device.
Authors:
D Gounot; Y Mauss; J Chambron
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Magma (New York, N.Y.)     Volume:  4     ISSN:  0968-5243     ISO Abbreviation:  MAGMA     Publication Date:    1996 Sep-Dec
Date Detail:
Created Date:  1997-09-22     Completed Date:  1997-09-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9310752     Medline TA:  MAGMA     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  195-204     Citation Subset:  IM    
Affiliation:
Institut de Physique Biolgique, Faculté de Médecine, Strasbourg, France.
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MeSH Terms
Descriptor/Qualifier:
Biometry
Europe
Gels
Humans
Magnetic Resonance Imaging / standards*,  statistics & numerical data
Magnetics
Phantoms, Imaging / standards*,  statistics & numerical data
Quality Control
Sepharose
Water
Chemical
Reg. No./Substance:
0/Gels; 7732-18-5/Water; 9012-36-6/Sepharose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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