| TNM staging, histopathological grading, and tumor-associated antigens in patients with a history of mucoepidermoid carcinoma of the salivary glands. | |
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MedLine Citation:
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PMID: 10470165 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The aim of this study was to evaluate the TNM categories and histopathological grading as prognostic factors in mucoepidermoid carcinoma (MEC). In addition, the study was designed to provide baseline data on levels of tumor-associated antigens (TAA) in sera of MEC patients. MATERIALS AND METHODS: Fifty-nine patients with MEC of the salivary glands were evaluated. RESULTS: Reclassified TNM stage, at the time of initial diagnosis, varied considerably. In disease-free patients, none of the tested sera were TAA elevated above the cut-off levels. Our patients who died of tumor metastasis had all been classified as stage III or IV at the time of initial diagnosis. Distant metastases are rarely found even decades after surgical therapy. CONCLUSIONS: Long-term follow-up is recommended for patients with MEC of the salivary glands. TAA are not elevated in disease-free patients. The value of TAA in the monitoring of MEC patients remains to be evaluated in further studies. |
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Authors:
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K Plambeck; R E Friedrich; M Bahlo; S Bartel-Friedrich; R Klapdor |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Anticancer research Volume: 19 ISSN: 0250-7005 ISO Abbreviation: Anticancer Res. Publication Date: 1999 Jul-Aug |
Date Detail:
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Created Date: 1999-09-28 Completed Date: 1999-09-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8102988 Medline TA: Anticancer Res Country: GREECE |
Other Details:
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Languages: eng Pagination: 2397-404 Citation Subset: IM |
Affiliation:
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Oral and Maxillofacial Surgery Clinic, Eppendorf University Hospital, University of Hamburg, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Antigens, Neoplasm / analysis* Carcinoma, Mucoepidermoid / classification, mortality, pathology*, surgery Child Disease-Free Survival Female Follow-Up Studies Humans Male Middle Aged Neoplasm Staging Retrospective Studies Salivary Gland Neoplasms / classification, mortality, pathology*, surgery Survival Analysis Time Factors Tumor Markers, Biological / analysis* |
| Chemical | |
Reg. No./Substance:
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0/Antigens, Neoplasm; 0/Tumor Markers, Biological |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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