Document Detail

TIMI risk score underestimates prognosis in unstable angina/non-ST segment elevation myocardial infarction.
MedLine Citation:
PMID:  17924227     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To determine the value of the TIMI risk score in the individual risk stratification of patients with unstable angina/non-ST segment elevation myocardial infarction (UA/NSTEMI). BACKGROUND: TIMI risk score is a validated tool to identify groups of patients at high risk for major cardiac events. Its prognostic value in individual patients with current diagnostic tools and therapy is unknown. METHODS: TIMI risk score was assessed in patients with UA/NSTEMI admitted to six Belgian hospitals and related to clinical outcome at 30 days. RESULTS: Of the 500 patients enrolled, 49.4% were placed in the low TIMI risk group (score = 0-3) and 50.6% in the high-risk group (score = 4-7). Multivariate analysis identified raised cardiac markers and invasive strategy, but not high TIMI risk score as independent predictors of death and new myocardial infarction (MI). Moreover, the incidence of death and MI in the low TIMI risk group with positive cardiac markers was not lower than in the high TIMI risk group with positive markers: 15.1% versus 17.8% (P = 0.7). CONCLUSIONS: TIMI risk score is of limited value for individual risk stratification. The presence of positive cardiac markers (troponin) appears to be a more powerful prognostic marker.
Anne Vorlat; Marc J Claeys; Herbert De Raedt; Sofie Gevaert; Yves Vandekerckhove; Philippe Dubois; Antoine De Meester; Christiaan Vrints
Related Documents :
15993647 - To examine the effectiveness of a hospital-based nurse-led secondary prevention clinic.
791467 - Application of step-wise discriminant analysis and bayesian classification procedure in...
8034867 - Prognostic significance of cardiac cinefluoroscopy for coronary calcific deposits in as...
7941507 - Cardiac evaluation and risk reduction in patients undergoing major vascular operations.
12767537 - Antiarrhythmic effect of magnesium sulfate after open heart surgery: effect of blood le...
16728877 - A new approach of primary angioplasty for st-elevation acute myocardial infarction base...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acute cardiac care     Volume:  10     ISSN:  1748-2941     ISO Abbreviation:  Acute Card Care     Publication Date:  2008  
Date Detail:
Created Date:  2008-05-01     Completed Date:  2008-09-23     Revised Date:  2009-11-17    
Medline Journal Info:
Nlm Unique ID:  101276603     Medline TA:  Acute Card Care     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  26-9     Citation Subset:  IM    
University Hospital Antwerp, Belgium.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Angina, Unstable / mortality*
Health Status Indicators
Middle Aged
Multivariate Analysis
Myocardial Infarction / mortality*
Risk Assessment

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Placenta increta after first-trimester dilatation and curettage manifesting as an unusual uterine ma...
Next Document:  In-hospital arrhythmias in patients with acute myocardial infarction - the relation to the reperfusi...