Document Detail

TIBA: A Tool for Phylogeny Inference from Rearrangement Data with Bootstrap Analysis.
MedLine Citation:
PMID:  23060619     Owner:  NLM     Status:  Publisher    
SUMMARY: TIBA is a tool to reconstruct phylogenetic trees from rearragement data which consists of ordered lists of synteny blocks (or genes) where each synteny block is shared with all of its homologs in the input genomes. The evolution of these synteny blocks, through rearrangement operations, is modeled by the uniform Double-Cut-and-Join model. Using a true distance estimate under this model and simple distance based methods TIBA reconstructs a phylogeny of the input genomes. Unlike any previous tool for inferring phylogenies from rearrangement data, TIBA uses novel methods of robustness estimation to provide support values for the edges in the inferred tree. AVAILABILITY: CONTACT:
Yu Lin; Vaibhav Rajan; Bernard Moret
Related Documents :
19476709 - Quantitative structure-retention relationship models for the prediction of the reversed...
18295489 - Qsar modeling of the rodent carcinogenicity of nitrocompounds.
16722649 - Skin permeation rate as a function of chemical structure.
18373549 - Computational study of the binding mode of epidermal growth factor receptor kinase inhi...
18415049 - New predictive models for blood-brain barrier permeability of drug-like molecules.
19182859 - Characterization of activity landscapes using 2d and 3d similarity methods: consensus a...
24051649 - Renovating animal facilities to withstand disasters.
16942119 - Accuracy versus transparency in pharmacoeconomic modelling: finding the right balance.
9660629 - Recent developments in computer-assisted analysis of mixtures.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-11
Journal Detail:
Title:  Bioinformatics (Oxford, England)     Volume:  -     ISSN:  1367-4811     ISO Abbreviation:  Bioinformatics     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9808944     Medline TA:  Bioinformatics     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Laboratory for Computational Biology and Bioinformatics, EPFL, EPFL-IC-LCBB INJ 230, Station 14, CH-1015 Lausanne, Switzerland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  DAFS: simultaneous aligning and folding of RNA sequences via dual decomposition.
Next Document:  Aragonite-associated biomineralization proteins are disordered and contain interactive motifs.