| THORACOSCORE fails to predict complications following elective lung resection. | |
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MedLine Citation:
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PMID: 22496319 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Thoracoscore mortality risk model has been incorporated into the British Thoracic Society guidelines on the radical management of patients with lung cancer. The discriminative and predictive ability to predict mortality and postoperative pulmonary complications (PPC) in this group of patients is uncertain.A prospective observational study was carried out on all patients following lung resection via thoracotomy in a regional thoracic centre over 42 months.128 of 703 subjects developed a PPC. 16 patients died in hospital (2%). In a logistic regression analysis the Thoracoscore was not a significant predictor of mortality (p=0.11; odds ratio (OR) =1.07, confidence interval (CI) 0.99-1.17) but was significant predictor of PPC (p=0.002; OR=1.08, CI 1.03-1.13). However, the area under the receiver operator characteristic (ROC) curve for the Thoracoscore was 0.68 (CI 0.56-0.80) for predicting mortality and 0.64 (CI 0.59-0.69) for PPC, indicating limited discriminative ability.In a logistic regression analysis, another risk model the European Society's Objective Score (ESOS) was predictive of mortality (p=0.006; OR =1.43, CI 1.11-1.83) and PPC (p<0.0001; OR =1.48, CI 1.30-1.68).Thoracoscore may have poor discriminative and predictive ability for mortality and PPC following elective lung resection. |
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Authors:
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A Bradley; A Marshall; M Abdelaziz; K Hussain; P Agostini; E Bishay; M Kalkat; R Steyn; P Rajesh; J Dunn; Babu Naidu |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-4-10 |
Journal Detail:
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Title: The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology Volume: - ISSN: 1399-3003 ISO Abbreviation: - Publication Date: 2012 Apr |
Date Detail:
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Created Date: 2012-4-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8803460 Medline TA: Eur Respir J Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Heart of England NHS Foundation Trust, Bordesley Green East, Birmingham, B9 5SS. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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