| A TAD better for myeloma therapy? | |
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MedLine Citation:
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PMID: 20150417 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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In this issue of Blood, Lokhorst and colleagues report on the results of HOVON-50, a phase 3 randomized trial designed to evaluate the effects of thalidomide during induction treatment and as maintenance in patients with multiple myeloma. There were 556 patients randomly assigned either to 3 cycles of VAD or to TAD. All patients were to receive high-dose melphalan with autologous stem cell support followed by maintenance with interferon for the VAD arm or thalidomide for the TAD arm.(1) This study together with other randomized and nonrandomized trials establish a definitive role for thalidomide as induction therapy in conjunction with dexamethasone, anthracyclines, and alkylating agents. |
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Authors:
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Sergio Giralt |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Blood Volume: 115 ISSN: 1528-0020 ISO Abbreviation: Blood Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-02-12 Completed Date: 2010-03-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7603509 Medline TA: Blood Country: United States |
Other Details:
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Languages: eng Pagination: 1109-10 Citation Subset: - |
Affiliation:
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M. D. Anderson Cancer Center, TX, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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