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T2D-nephropathy linkage within 12q24 locus.
MedLine Citation:
PMID:  21439668     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The 12q24 locus is linked to microcirculation pathology and type 2 diabetes (T2D) with nephropathy and entails the PSMD9 gene linked to T2D. We tested the PSMD9 T2D risk SNPs IVS3+nt460A>G, IVS3+nt437T>C and E197G for linkage to T2D-diabetic nephropathy in 200 Italians T2D families and show linkage to diabetic nephropathy.
Authors:
Claudia Gragnoli
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-23
Journal Detail:
Title:  Diabetes research and clinical practice     Volume:  -     ISSN:  1872-8227     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508335     Medline TA:  Diabetes Res Clin Pract     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011. Published by Elsevier Ireland Ltd.
Affiliation:
Laboratory of Molecular Genetics of Complex and Monogenic Disorders, Department of Medicine and Cellular & Molecular Physiology and Biostatistics, H044, M.S. Hershey Medical Center, Penn State University College of Medicine, 500 University Drive, Hershey, PA, USA; Center for Biotechnology and Department of Biology, Temple University's College of Science & Technology, Philadelphia, PA, USA; Molecular Biology Laboratory, Bios Biotech Multi-Diagnostic Health Center, Rome, Italy.
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