| T2* measurements in human brain at 1.5, 3 and 7 T. | |
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MedLine Citation:
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PMID: 17459640 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Measurements have been carried out in six subjects at magnetic fields of 1.5, 3 and 7 T, with the aim of characterizing the variation of T2* with field strength in human brain. Accurate measurement of T2* in the presence of macroscopic magnetic field inhomogeneity is problematic due to signal decay resulting from through-slice dephasing. The approach employed here allowed the signal decay due to through-slice dephasing to be characterized and removed from data, thus facilitating an accurate measurement of T2* even at ultrahigh field. Using double inversion recovery turbo spin-echo images for tissue classification, an analysis of T2* relaxation times in cortical grey matter and white matter was carried out, along with an evaluation of the variation of T2* with field strength in the caudate nucleus and putamen. The results show an approximately linear increase in relaxation rate R2* with field strength for all tissues, leading to a greater range of relaxation times across tissue types at 7 T that can be exploited in high-resolution T2*-weighted imaging. |
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Authors:
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Andrew M Peters; Matthew J Brookes; Frank G Hoogenraad; Penny A Gowland; Susan T Francis; Peter G Morris; Richard Bowtell |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2007-04-25 |
Journal Detail:
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Title: Magnetic resonance imaging Volume: 25 ISSN: 0730-725X ISO Abbreviation: Magn Reson Imaging Publication Date: 2007 Jul |
Date Detail:
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Created Date: 2007-07-27 Completed Date: 2007-11-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8214883 Medline TA: Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 748-53 Citation Subset: IM |
Affiliation:
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Sir Peter Mansfield Magnetic Resonance Center, School of Physics and Astronomy, University of Nottingham, NG7 2RD Nottingham, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Brain / pathology* Brain Diseases Brain Mapping / methods Caudate Nucleus / pathology Cerebrovascular Circulation Electromagnetic Fields Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging / methods* Models, Statistical Putamen / pathology Reference Values Research Design |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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