| T(2) determination of the J-coupled methyl protons of lipids: In vivo ilustration with tibial bone marrow at 3 T. | |
| | |
MedLine Citation:
|
PMID: 20512909 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To demonstrate how J-coupling modulations of the CH(3) lipid resonance can be minimized enabling a representative T(2) to be measured. MATERIALS AND METHODS: Experiments were conducted on canola oil and in vivo on tibial bone marrow of four volunteers at 3 T. The T(2) of the CH(2) protons was measured with a standard point resolved spectroscopy (PRESS) sequence, whereas the T(2) of the CH(3) protons was determined with a PRESS sequence composed of narrow bandwidth refocusing pulses designed to exploit the chemical shift displacement effect and rewind the J-coupling evolution of the CH(3) protons in the desired voxel. Spectra were acquired at five echo times. RESULTS: The narrow bandwidth PRESS sequence rewound the J-evolution of the CH(3) protons resulting in a T(2) curve that was well described by a monoexponential function. The mean T(2) of the bone marrow CH(3) protons was calculated to be 132.6 msec. The mean T(2) of the bone marrow CH(2) protons was estimated with a regular PRESS sequence to be 88.0 msec. The mean CH(2):CH(3) tibial bone marrow composition was estimated to be 12.0:1. CONCLUSION: The presented technique permits the T(2) of the methyl protons of lipids to be determined with more accuracy by minimizing contributions from J-coupling. |
| | |
Authors:
|
Atiyah Yahya; B Gino Fallone |
Related Documents
:
|
19923699 - Cluster analyses of metal-organic fragments using the dsnap software. 11666239 - Synthesis of polysiloxane-bound (ether-phosphine)palladium complexes. stoichiometric an... 22364289 - Nitrile imines: matrix isolation, ir spectra, structures, and rearrangement to carbodii... 18688839 - 1,4-dicyanobenzene as a scaffold for the preparation of bimetallic actinide complexes e... 20888749 - Influence of aeration on ch4, n2o and nh3 emissions during aerobic composting of a chic... 22517189 - Designing organometallic compounds for catalysis and therapy. 21945209 - H(2)s gas biological removal efficiency and bacterial community diversity in biofilter ... 20355179 - Computational and vibrational spectroscopic studies of ipratropium bromide. 9023979 - Synthesis and biological activity of a 1 alpha,25-dihydroxyvitamin d2 analog bearing an... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Journal of magnetic resonance imaging : JMRI Volume: 31 ISSN: 1522-2586 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2010 Jun |
Date Detail:
|
Created Date: 2010-05-31 Completed Date: 2010-09-28 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
|
Languages: eng Pagination: 1514-21 Citation Subset: IM |
Affiliation:
|
Department of Medical Physics, Cross Cancer Institute, Edmonton, Alberta, Canada T6G 1Z2. ayahya@ualberta.ca |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Bone Marrow
/
pathology* Humans Image Processing, Computer-Assisted Lipids / chemistry* Magnetic Resonance Spectroscopy / methods* Phantoms, Imaging Protons Tibia / pathology* |
| Chemical | |
Reg. No./Substance:
|
0/Lipids; 0/Protons |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Low-intensity pulsed ultrasound increases cellular uptake of superparamagnetic iron oxide nanomateri...
Next Document: Stimulated echo induced misestimates on diffusion tensor indices and its remedy.