Document Detail


T1-weighted-SPACE dark blood whole body magnetic resonance angiography (DB-WBMRA): initial experience.
MedLine Citation:
PMID:  20099365     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To evaluate the feasibility of the dark blood fast spin echo (FSE) T1-weighted-Sampling Perfection with Application of optimized Contrasts using different flip angle Evolution (T1w-SPACE) sequence in assessing whole body arterial wall information from the extracranial carotids to the popliteal artery. MATERIALS AND METHODS: Twenty-eight subjects were subjected to noncontrast, dark blood whole body magnetic resonance angiography (DB-WBMRA) using a T1w-SPACE sequence optimized for each of the individual stations: carotid artery, thoracic aorta, abdominal aorta, and thigh/superficial femoral artery (SFA). Image quality/vessel wall visualization and the time required to image the four stations were evaluated. Two observers checked the reproducibility of vessel wall depiction by performing quantitative measurements in registered initial and repeat studies (six subjects) of vessel wall and lumen area at 17 locations along the arterial tree. RESULTS: In 25 of the 28 scanned subjects, dark blood arterial images acquired in approximately 1 hour total imaging time allowed whole body arterial vessel wall visualization. Quantitative measurements showed high correlation between the initial and repeat studies for each of the observers as well as high interobserver reproducibility (r > 0.95; P < 0.01). CONCLUSION: DB-WBMRA using T1w-SPACE is feasible and can be performed with a high degree of reliability.
Authors:
Georgeta Mihai; Yiu-Cho Chung; Ali Merchant; Orlando P Simonetti; Sanjay Rajagopalan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  31     ISSN:  1522-2586     ISO Abbreviation:  J Magn Reson Imaging     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-01-29     Completed Date:  2010-04-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  502-9     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA. georgeta.mihai@osumc.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Algorithms*
Carotid Arteries / anatomy & histology*
Feasibility Studies
Female
Humans
Image Enhancement / methods*
Image Interpretation, Computer-Assisted / methods*
Magnetic Resonance Angiography / methods*
Male
Middle Aged
Pilot Projects
Reproducibility of Results
Sensitivity and Specificity
Subtraction Technique*
Whole Body Imaging / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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