| T1 assessment of hip joint cartilage following intra-articular gadolinium injection: a pilot study. | |
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MedLine Citation:
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PMID: 20872764 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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This pilot study defines the feasibility of cartilage assessment in symptomatic femoroacetabular impingement patients using intra-articular delayed gadolinium-enhanced MRI of cartilage (ia-dGEMRIC). Nine patients were scanned preliminary to study the contrast infiltration process into hip joint cartilage. Twenty-seven patients with symptomatic femoroacetabular impingement were subsequently scanned with intra-articular delayed gadolinium-enhanced MRI of cartilage. These T(1) findings were correlated to morphological findings. Zonal variations were studied. This pilot study demonstrates a significant difference between the pre- and postcontrast T(1) values (P < 0.001) remaining constant for 45 min. We noted higher mean T(1) values in morphologically normal-appearing cartilage than in damaged cartilage, which was statistically significant for all zones except the anterior-superior zone. Intraobserver (0.972) and interobserver correlation coefficients (0.933) were statistically significant. This study outlines the feasibility of intra-articular delayed gadolinium-enhanced MRI of cartilage for assessment of cartilage changes in patients with femoroacetabular impingement. It can also define the topographic extent and differing severities of cartilage damage. |
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Authors:
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Bernd Bittersohl; Harish S Hosalkar; Young-Jo Kim; Stefan Werlen; Siegfried Trattnig; Klaus A Siebenrock; Tallal C Mamisch |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Volume: 64 ISSN: 1522-2594 ISO Abbreviation: Magn Reson Med Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8505245 Medline TA: Magn Reson Med Country: United States |
Other Details:
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Languages: eng Pagination: 1200-7 Citation Subset: IM |
Affiliation:
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Department of Orthopedic Surgery, Inselspital, Bern, Switzerland. bbittersohl@partners.org |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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