Document Detail

T wave abnormalities in top-ranking athletes: effects of isoproterenol, atropine, and physical exercise.
MedLine Citation:
PMID:  6447450     Owner:  NLM     Status:  MEDLINE    
Eight cases of top-ranking athletes with "repolarization disorders" are reported. All subjects were asymptomatic and were otherwise suited for excellent cardiovascular performances. Seven athletes did not show any evidence of heart disease. Seven had MVP (mitral valve prolapse). Umprompted variability of ECG tracings was observed in three cases. Both isoproterenol infusions (IS) and maximal physical effort (EX) normalized T wave (abnormalities in 100% of cases, while atropine (AT) was ineffective despite an increase in heart rate greater than that caused by IS. The authors emphasize the usefulness of combined use of the EX and IS tests in ascertaining the clinical significance of T wave changes in healthy athletes. A "neurogenic" mechanism is proposed by the authors for the pathogenesis of these T wave abnormalities. This hypothesis may explain the umprompted variability of ECG tracings and T wave normalization after maximal physical effort and isoproterenol infusion.
P Zeppilli; M M Pirrami; M Sassara; R Fenici
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  100     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1980 Aug 
Date Detail:
Created Date:  1980-10-24     Completed Date:  1980-10-24     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  213-22     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Atropine / pharmacology*
Bradycardia / diagnosis
Cardiomegaly / diagnosis
Hyperventilation / diagnosis
Isoproterenol / pharmacology*
Physical Exertion / drug effects*
Valsalva Maneuver
Reg. No./Substance:
51-55-8/Atropine; 7683-59-2/Isoproterenol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Spontaneous production of mediators by mononuclear human blood cells (author's transl)
Next Document:  Ultrastructural study of a blood-muscle spindle barrier after systemic administration of horseradish...