Document Detail


T-lymphocyte subsets and thymic size in malnourished infants in Egypt: a hospital-based study.
MedLine Citation:
PMID:  18290395     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Thymus size was assessed ultrasonographically and correlated to the percentage of CD4 and CD8 T-lymphocytes in peripheral blood in 32 infants with protein-energy malnutrition (PEM) and compared with 14 healthy control infants. The study revealed thymus atrophy in patients with PEM, especially the oedematous type, accompanied by changes in the peripheral lymphocyte subsets. These changes were reversible after nutritional rehabilitation. However, they may affect the immune status of PEM patients and may require a longer duration of nutrition rehabilitation than required for recovery of anthropometric measures. We recommend proper assessment of the immune functions of PEM patients during nutritional rehabilitation until full recovery.
Authors:
M F Nassar; N T Younis; A G Tohamy; D M Dalam; M A El Badawy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Eastern Mediterranean health journal = La revue de santé de la Méditerranée orientale = al-Majallah al-ṣiḥḥīyah li-sharq al-mutawassiṭ     Volume:  13     ISSN:  1020-3397     ISO Abbreviation:  East. Mediterr. Health J.     Publication Date:    2007 Sep-Oct
Date Detail:
Created Date:  2008-02-22     Completed Date:  2008-03-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9608387     Medline TA:  East Mediterr Health J     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  1031-42     Citation Subset:  IM    
Affiliation:
Department of Paediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt. maie_nassar@yahoo.co.uk
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MeSH Terms
Descriptor/Qualifier:
Anthropometry
Atrophy
CD4-Positive T-Lymphocytes / metabolism
CD8-Positive T-Lymphocytes / metabolism
Case-Control Studies
Dietary Proteins / administration & dosage
Edema / etiology
Egypt
Energy Intake
Female
Flow Cytometry
Hospitals, Pediatric
Humans
Infant
Lymphocyte Count
Male
Nutrition Assessment
Protein-Energy Malnutrition / blood*,  complications,  diagnosis*,  immunology,  rehabilitation
Serum Albumin / metabolism
Statistics, Nonparametric
T-Lymphocyte Subsets / metabolism*
Thymus Gland / pathology*,  ultrasonography
Treatment Outcome
Chemical
Reg. No./Substance:
0/Dietary Proteins; 0/Serum Albumin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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