Document Detail


T lymphocyte subsets in chronic AgHBe positive hepatitis and the effects of prednisone therapy.
MedLine Citation:
PMID:  2135834     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
T lymphocyte subsets were studied in 18 patients with chronic AgHBe positive hepatitis. The study was carried out before, during and after a ten week course of prednisone therapy. There was no statistically significant difference during and after prednisone therapy in patients with hepatitis as to the total lymphocyte number and T lymphocyte subsets. The CD4/CD8 ratio was significantly decreased when compared with that of the normal controls, as the result of a reduction in CD4 T lymphocyte population before the beginning of the therapy. The patients did not respond to prednisone therapy.
Authors:
R Mattar; L E da Fonseca; L C da Silva
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Revista do Hospital das Clínicas     Volume:  45     ISSN:  0041-8781     ISO Abbreviation:  Rev Hosp Clin Fac Med Sao Paulo     Publication Date:    1990 Nov-Dec
Date Detail:
Created Date:  1992-07-23     Completed Date:  1992-07-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0415246     Medline TA:  Rev Hosp Clin Fac Med Sao Paulo     Country:  BRAZIL    
Other Details:
Languages:  eng     Pagination:  244-7     Citation Subset:  IM; X    
Affiliation:
Department of Gastroenterology, Hospital das Clínicas de São Paulo.
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MeSH Terms
Descriptor/Qualifier:
CD4-CD8 Ratio*
Double-Blind Method
Female
Hepatitis B / drug therapy*,  immunology
Hepatitis B e Antigens / analysis
Humans
Male
Prednisone / administration & dosage,  therapeutic use*
T-Lymphocyte Subsets*
Chemical
Reg. No./Substance:
0/Hepatitis B e Antigens; 53-03-2/Prednisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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