Document Detail


T cell lymphopenia in Nigerians with hepatocellular carcinoma.
MedLine Citation:
PMID:  2176539     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Lymphocyte sub-populations were studied in 26 Nigerian patients with primary hepatocellular carcinoma (PLCC) and in 12 normal controls. The 3H-thymidine incorporation of lymphocytes from patients and controls was also studied on phytohaemagglutinin (PHA) stimulation. Total mean lymphocyte and B-cell lymphocyte counts were not different between patients and controls. The mean T cell percentages and absolute counts were significantly lower in patients than in controls. There was a significant elevation of null cell numbers and percentage in PLCC patients. Lymphocytes from patients and controls gave similar response on PHA stimulation.
Authors:
G C Onyemelukwe; G O Oyeyinka; I I Onyewotu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  West African journal of medicine     Volume:  9     ISSN:  0189-160X     ISO Abbreviation:  West Afr J Med     Publication Date:    1990 Apr-Jun
Date Detail:
Created Date:  1991-02-19     Completed Date:  1991-02-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8301891     Medline TA:  West Afr J Med     Country:  NIGERIA    
Other Details:
Languages:  eng     Pagination:  79-82     Citation Subset:  IM    
Affiliation:
Department of Medicine, Ahmadu Bello University Teaching Hospital, Zaria.
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MeSH Terms
Descriptor/Qualifier:
Adult
B-Lymphocytes / chemistry
Carcinoma, Hepatocellular / complications*
Humans
Leukopenia / blood*,  etiology
Liver Neoplasms / complications*
Middle Aged
T-Lymphocytes / chemistry*

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