| T and B lymphocytes during normal human pregnancy: a longitudinal study. | |
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MedLine Citation:
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PMID: 317536 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Immunological relationships in pregnancy were investigated in a longitudinal study of twenty-two pregnant women, whose blood samples were taken before pregnancy, during pregnancy, at delivery, and 3--5 months after delivery. Blood samples were also taken from the fathers and the infants, both at birth and after 3--5 months. All the samples were frozen by means of a cryobiological freezing system, and when a whole longtiudinal series had been collected, the material was thawed and tested in a single seance. T and B lymphocytes were studied with rosette tests (E and HEAC rosettes). T and B lymphocytes were found not to change during the course of pregnancy. It is thus concluded that the mother's tolerance of a fetus with a dissimilar tissue type is not exercised via changes in the total count of T and B lymphocytes, although there may well be changes in their subpopulations, with the hypothesis that T-suppressor function increases and B-lymphocyte function decreases. |
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Authors:
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S A Birkeland; K Kristoffersen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Scandinavian journal of immunology Volume: 10 ISSN: 0300-9475 ISO Abbreviation: Scand. J. Immunol. Publication Date: 1979 |
Date Detail:
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Created Date: 1980-07-28 Completed Date: 1980-07-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0323767 Medline TA: Scand J Immunol Country: NORWAY |
Other Details:
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Languages: eng Pagination: 415-9 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult B-Lymphocytes / immunology* Blood Specimen Collection Female Gestational Age Humans Infant Infant, Newborn Leukocyte Count Longitudinal Studies Male Pregnancy* Rosette Formation T-Lymphocytes / immunology* |
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