Document Detail

Systolic tissue velocity is a useful echocardiographic parameter in assessment of left atrial appendage function in patients with mitral stenosis.
MedLine Citation:
PMID:  17767531     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The incidence of thromboembolism remains high in patients with mitral stenosis (MS). The left atrial appendage (LAA) is a potential site for development of thrombus and LAA dysfunction is an independent predictor of thromboembolism. The LAA dysfunction is represented by reduced LAA late emptying velocity. But the magnitude of LAA flow velocities is dependent on acute changes in loading conditions. AIM: To investigate the value of the LAA tissue velocities obtained by tissue Doppler imaging (TDI) in assessment of LAA function in MS patients with and without thromboembolic events. METHODS: The study population consisted of 98 isolated MS patients of 32 age and sex-matched healthy controls. All subjects underwent transesophageal echocardiography (TEE). LAA late peak emptying (LAAEV) and filling (LAAFV) flow velocities were recorded. LAA peak late tissue systolic (LSV) and diastolic (LDV) tissue velocities by TDI were measured. The patients were divided into three groups as Group I (n = 38, sinus rhythm and LAAEV > or = 25 cm/s), Group II (n = 26, sinus rhythm and LAAEV < 25 cm/s), and Group III (n = 34, atrial fibrillation). RESULTS: Twenty-one patients had thromboembolic events. LAAEV, LAAFV, LSV, and LDV were significantly reduced in patients with embolic events. Spontaneous echo contrast (SEC) density was strongly negative correlated with LSV, whereas weakly negative correlated with LAAEV. Multivariate regression analysis showed that LSV and the presence of SEC were independently associated with embolic events. CONCLUSION: LSV seems more reliable and useful parameter in evaluating LAA function. LAA function is more depressed among patients with embolic events.
Murat Cayli; Esmeray Acartürk; Mesut Demir; Mehmet Kanadaşi
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Echocardiography (Mount Kisco, N.Y.)     Volume:  24     ISSN:  0742-2822     ISO Abbreviation:  Echocardiography     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-09-04     Completed Date:  2008-01-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8511187     Medline TA:  Echocardiography     Country:  United States    
Other Details:
Languages:  eng     Pagination:  816-22     Citation Subset:  IM    
Department of Cardiology, School of Medicine, Cukurova University, Adana 01330, Turkey.
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MeSH Terms
Analysis of Variance
Atrial Appendage / physiopathology*,  ultrasonography
Atrial Function, Left / physiology*
Echocardiography, Transesophageal
Logistic Models
Middle Aged
Mitral Valve Stenosis / physiopathology*,  ultrasonography
Observer Variation
ROC Curve

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