| Systolic and diastolic function in patients with systemic sclerosis. | |
| | |
MedLine Citation:
|
PMID: 19524178 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Clinical and epidemiological findings indicate that symptomatic heart disease in patients with systemic sclerosis (SSc) predicts poor prognosis, but cardiac involvement may occur years before clinical manifestation. The aim of this study was to evaluate the cardiac function in patients with SSc and to correlate the echocardiographic parameters with others that quantify the diseases' severity. METHODS: Twenty consecutive patients with SSc were investigated with transthoracic echocardiography (TTE). Two dimensional, pulsed Doppler and pulsed tissue Doppler imaging (TDI) techniques were used, in all the patients, to assess the systolic and diastolic function for left ventricle (LV). Correlations were made between echocardiographic measurements and some clinical and serological features of the patients. RESULTS: None of the patients had any clinical signs of cardiac involvement, nor ECG or TTE systolic function impairment; there are significant differences between systemic sclerosis patients and control group for peak A velocity (0.75+/-0.22 vs 0.57+/-0.32, P=0.05), E/A ratio (1.14+/-0.22 vs 1.48+/-0.26, P=0.01), E/Ea ratio (8.25+/-1.57 vs 7+/-2.2, P=0.05), which account for filling impairment of LV. There are also significant correlations between some other parameters, like the mean duration of Raynaud's phenomenon and E/Ea ratio (r=0.48, P<0.05). CONCLUSIONS: The analysis of SSc heart disease, mainly at a preclinical level, is important in all the cases as an asymptomatic patient may have diastolic dysfunction which can be treated and should be closely observed. |
| | |
Authors:
|
Laura Poanta; Razvan Dadu; Cristina Tiboc; Simona Rednic; Dan Dumitrascu |
Related Documents
:
|
12907548 - Left ventricular hypertrophy is a common echocardiographic abnormality in severe obstru... 18328858 - Association of sleep-disordered breathing and ventricular arrhythmias in patients witho... 21997588 - Diagnostic efficiency of the cochlear hydrops analysis masking procedure in ménière's... 17584728 - Twenty-millisecond interventricular difference as assessed by body surface potential ma... 9598678 - Early transoesophageal echocardiography in cryptogenic and lacunar stroke and transient... 19875408 - Rationale and design of ferinject assessment in patients with iron deficiency and chron... |
Publication Detail:
|
Type: Journal Article Date: 2008-11-29 |
Journal Detail:
|
Title: European journal of internal medicine Volume: 20 ISSN: 1879-0828 ISO Abbreviation: Eur. J. Intern. Med. Publication Date: 2009 Jul |
Date Detail:
|
Created Date: 2009-06-15 Completed Date: 2009-09-01 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9003220 Medline TA: Eur J Intern Med Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 378-82 Citation Subset: IM |
Affiliation:
|
University of Medicine and Pharmacy Iuliu Hatieganu, 2nd Medical Department, Cluj Napoca, Romania. laurapoanta@yahoo.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Diastole Echocardiography Echocardiography, Doppler Female Humans Male Middle Aged Prognosis Raynaud Disease / etiology, physiopathology, ultrasonography Scleroderma, Systemic / complications*, physiopathology* Systole Ventricular Dysfunction, Left* / etiology, physiopathology, ultrasonography Ventricular Function, Left* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Risk factors for cardiovascular disease in Sardinia from 1978 to 2001: a comparative study with Ital...
Next Document: High levels of tumor markers in pleural fluid correlate with poor survival in patients with adenocar...