Document Detail


Systemic thrombolysis using tissue plasminogen activator for a patient with paradoxic embolism: a case report.
MedLine Citation:
PMID:  17463205     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
When thrombotic material that originates from deep venous thrombosis of the lower extremities is washed out into the pulmonary vasculature, pulmonary embolization occurs. Pulmonary embolism and associated acute peripheral ischemia suggest the diagnosis of paradoxic embolism, which is most often associated with a patent foramen ovale. Therapeutic options include anticoagulation, mechanical/chemical thrombus dissolution, inferior vena cava filtration, and closure of the intracardiac defect. The diagnosis and treatment are described of an elderly female who presented with lower extremity deep venous thrombosis and massive pulmonary embolism complicated by paradoxic emboli to the left subclavian artery as well as the celiac artery.
Authors:
Zhen Fan; Richard Roedersheimer; Joann Lohr
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Vascular and endovascular surgery     Volume:  41     ISSN:  1538-5744     ISO Abbreviation:  Vasc Endovascular Surg     Publication Date:    2007 Apr-May
Date Detail:
Created Date:  2007-04-27     Completed Date:  2007-10-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136421     Medline TA:  Vasc Endovascular Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  136-9     Citation Subset:  IM    
Affiliation:
Department of Surgery, Good Samaritan Hospital, Cincinnati, Ohio 45220, USA. Joy_Rusche@trihealth.com
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MeSH Terms
Descriptor/Qualifier:
Aged, 80 and over
Aorta, Thoracic / pathology,  surgery
Celiac Artery / pathology,  surgery
Embolism, Paradoxical / complications,  drug therapy*,  radiography,  surgery
Female
Femoral Vein / pathology,  surgery
Fibrinolytic Agents / therapeutic use*
Heart Septal Defects, Atrial / surgery
Humans
Pulmonary Embolism / drug therapy*,  etiology,  radiography,  surgery
Subclavian Artery / pathology,  surgery
Tissue Plasminogen Activator / therapeutic use*
Tomography, X-Ray Computed
Ultrasonography, Doppler
Vascular Surgical Procedures
Venous Thrombosis / drug therapy
Chemical
Reg. No./Substance:
0/Fibrinolytic Agents; EC 3.4.21.68/Tissue Plasminogen Activator

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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