Document Detail

Systemic therapy for cardiac sarcomas.
MedLine Citation:
PMID:  20834213     Owner:  NLM     Status:  MEDLINE    
Cardiac sarcomas create 2 risks: local problems and metastatic disease. Most frequently, the histologies are angiosarcoma and high-grade pleomorphic unclassified sarcoma (formerly called MFH or malignant fibrous histiocytoma). There is also a clinical-pathological entity without distinctive histological features of tumors that originate in the pulmonary artery and are referred to as pulmonary artery sarcomas or intimal sarcomas of the pulmonary artery. Conventional wisdom indicates that soft-tissue sarcomas are poorly responsive to chemotherapy. Luckily, that is not the case. Attempts to concentrate on the local problem only with therapies up to and including cardiac transplantation have been unsuccessful due to the high rate of fatal metastatic disease.
Vinod Ravi; Robert S Benjamin
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Publication Detail:
Type:  Journal Article; Portraits    
Journal Detail:
Title:  Methodist DeBakey cardiovascular journal     Volume:  6     ISSN:  1947-6094     ISO Abbreviation:  Methodist Debakey Cardiovasc J     Publication Date:    2010 Jul-Sep
Date Detail:
Created Date:  2010-09-13     Completed Date:  2010-11-23     Revised Date:  2012-08-17    
Medline Journal Info:
Nlm Unique ID:  101508600     Medline TA:  Methodist Debakey Cardiovasc J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  57-60     Citation Subset:  IM    
The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
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MeSH Terms
Antineoplastic Agents / administration & dosage,  adverse effects,  therapeutic use*
Heart Neoplasms / diagnosis,  drug therapy*
Sarcoma / diagnosis,  drug therapy*
Treatment Outcome
Reg. No./Substance:
0/Antineoplastic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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