| Systemic therapy of New World cutaneous leishmaniasis: A case report and review article. | |
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MedLine Citation:
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PMID: 21629609 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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Cutaneous leishmaniasis is a disease endemic to Central and South America, Mexico and the Caribbean, and affects millions of people. As travel to these regions becomes more common, cutaneous leishmaniasis is becoming a disease of increasing importance in the developed world. However, disease recognition and access to appropriate therapy for cutaneous leishmaniasis remains a challenge in North America. The present article reports a case of cutaneous leishmaniasis in a Canadian man following a trip to Costa Rica. Species-specific diagnosis was confirmed by polymerase chain reaction analysis of a skin biopsy, which was positive for Leishmania panamensis. After failing a course of itraconazole, the patient was successfully treated with sodium stibogluconate, despite significant barriers to administering this therapy, and the paucity of data regarding its efficacy and tolerability. The pathophysiology, diagnosis and systemic treatment of cutaneous leishmaniasis, as well as its emerging presence in the developed world, are reviewed. |
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Authors:
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Amir Abadir; Ameen Patel; Shariq Haider |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie médicale / AMMI Canada Volume: 21 ISSN: 1918-1493 ISO Abbreviation: Can J Infect Dis Med Microbiol Publication Date: 2010 |
Date Detail:
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Created Date: 2011-06-01 Completed Date: 2011-07-14 Revised Date: 2011-07-28 |
Medline Journal Info:
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Nlm Unique ID: 101226876 Medline TA: Can J Infect Dis Med Microbiol Country: Canada |
Other Details:
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Languages: eng Pagination: e79-83 Citation Subset: - |
Affiliation:
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Department of Medicine; |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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