Document Detail


Systemic and regional blood flows during graded treadmill exercise in dogs.
MedLine Citation:
PMID:  3572828     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of the study was to describe hemodynamic response and regional blood flows through various organs and tissues (microsphere technique) in dogs (n = 8), at rest and during mild (4 km/h, 13% slope; heart rate = 154 bpm), moderate (4 km/h, 26% slope; heart rate = 201 bpm), and severe (4 km/h, 39% slope; heart rate = 266 bpm) exercise on treadmill. Cardiac output (rest: 3.2 +/- 0.3; 39% slope: 10.2 +/- 1.3 l/min; mean +/- SE), systolic aortic pressure (rest: 122 +/- 4; 39% slope: 158 +/- 9 mm Hg), and left atrial pressure (rest: 5 +/- 0.7; 39% slope: 11.0 +/- 0.6 mm Hg) increased linearly with workload. On the contrary stroke volume increased from rest (35 +/- 2 ml) to mild (38 +/- 2 ml) and moderate (42 +/- 3 ml) exercise but decreased in response to the severe workload (38 +/- 5 ml). Regional blood flows across the brain, femoral bone, adrenal glands and temporalis muscle were not modified during exercise. On the contrary, a marked increase in regional blood flow was observed through the flexor and extensor muscles of the limb (X 5 to X 15), the muscles of the back (X 4) and the diaphragm (X 2.5). The small inconsistent increase in nutritional tongue blood flow probably underestimated the increased perfusion through arteriovenous shunts in the mucosa for heat-loss purposes. Myocardial blood flow increased in a linear fashion with work load in both ventricles.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
J Y Pagny; F Peronnet; L Beliveau; F Sestier; R Nadeau
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal de physiologie     Volume:  81     ISSN:  0021-7948     ISO Abbreviation:  J. Physiol. (Paris)     Publication Date:  1986  
Date Detail:
Created Date:  1987-06-17     Completed Date:  1987-06-17     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9309350     Medline TA:  J Physiol (Paris)     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  368-73     Citation Subset:  IM; S    
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Circulation*
Blood Pressure
Cardiac Output
Dogs
Heart Rate
Hemodynamics*
Organ Specificity
Physical Exertion*
Posture
Regional Blood Flow

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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