Document Detail

Systemic lupus erythematosus: a unique cause of central cord syndrome, a case report.
MedLine Citation:
PMID:  10752868     Owner:  NLM     Status:  MEDLINE    
Central cord syndrome has classically been defined by disproportionately more motor impairment of the upper than the lower extremities, bladder dysfunction, and varying degrees of sensory loss below the level of the lesion. Review of the literature indicates that the majority of causes of central cord syndrome have a traumatic etiology and few are a consequence of connective tissue disorders. This is a case of a 53-year-old female with systemic lupus erythematosus who developed central cord syndrome due to an exacerbation of her disease. The patient presented with upper extremity motor and sensory deficits but only sensory deficits of the lower extremities. She had laboratory abnormalities consistent with lupus, and magnetic resonance imaging of the cervical spine revealed decreased attenuation from C-1-T-2. High-dose intravenous steroids were started in the acute care hospital with some return of proximal upper extremity strength. Upon transfer to the acute rehabilitation unit, the patient was noted to have neurogenic bladder dysfunction requiring a catheterization program. The patient was slowly tapered down on her oral prednisone with minimal improvement of strength but with return of bladder function. A review of the literature revealed few cases of central cord syndrome secondary to a connective tissue disorder or a non-traumatic etiology.
R D Ramos; W L Bockenek
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The journal of spinal cord medicine     Volume:  23     ISSN:  1079-0268     ISO Abbreviation:  J Spinal Cord Med     Publication Date:  2000  
Date Detail:
Created Date:  2000-05-25     Completed Date:  2000-05-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9504452     Medline TA:  J Spinal Cord Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  10-4     Citation Subset:  IM    
Charlotte Institute of Rehabilitation, Department of Physical Medicine and Rehabilitation, North Carolina 28203, USA.
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MeSH Terms
Central Cord Syndrome / diagnosis*
Cervical Vertebrae / pathology
Diagnosis, Differential
Lupus Erythematosus, Systemic / diagnosis*
Magnetic Resonance Imaging
Middle Aged
Neurologic Examination
Spinal Cord
Urinary Bladder, Neurogenic / diagnosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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