Document Detail

Systemic lupus erythematosus and transient left ventricular noncompaction.
MedLine Citation:
PMID:  24863427     Owner:  NLM     Status:  Publisher    
Objectives. Myocarditis is a rare but serious manifestation of patients with systemic lupus erythematosus (SLE). Left ventricular noncompaction (LVNC) is a disorder of myocardial morphogenesis frequently associated to neuromuscular diseases. Hypertrabeculation, a cardinal echocardiographic feature of LVNC, might represent a morphological expression of a number of morbidities, nevertheless. The relationship of LVNC with connective tissue disorders such as SLE is unknown. We aim to present a case of a patient with SLE who recently showed features compatible with an atypical LVNC. Methods. To report a case of a young female with a 10-year history of SLE who developed haematological disease activity and cardiac failure. Results. Ecocardiography showed hypertrabeculation/noncompaction, a very low ejection fraction and pulmonary hypertension. Clinical and echocardiographic features reverted with standard treatment for SLE activity and cardiac insufficiency. Conclusion. The transitory aspect of the cardiomyopathy made unlikely a "true" LVNC for this patient, but she might have presented a lupus myocarditis with "LVNC-like" features. The occurrence of hypertrabeculated myocardium in patients with SLE warrants further studies.
Cristina Ferreira Rabelo; Fabio Batistella; Ronaldo Nunes Godinho; Tiago Santini Machado; Flavio José Petersen Velho; Henrique Luiz Staub
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-10-15
Journal Detail:
Title:  Acta reumatologica portuguesa     Volume:  -     ISSN:  0303-464X     ISO Abbreviation:  Acta Reumatol Port     Publication Date:  2013 Oct 
Date Detail:
Created Date:  2014-5-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0431702     Medline TA:  Acta Reumatol Port     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Vernacular Title:
Systemic lupus erythematosus and transient left ventricular noncompaction.
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