| Systemic lupus erythematosus and pregnancy. | |
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MedLine Citation:
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PMID: 20121497 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We present a retrospective study of 42 consecutive cases of systemic lupus erythematosus (SLE) and pregnancy followed and delivered during the period 2002-2007 in our department. The mean patient age was 28.6 years and the nulliparity rate was 45.2%. Disease flare up occurred in 9.5% of patients. Lupus anticoagulants, anticardiolipin IgG and IgM antibodies were positive in 33%, 16.6% and 19% of patients, respectively. Mean gestational age at delivery was 36.9 +/- 4.2 and mean birth weight was 2,750 +/- 844 g. Stillbirth, fetal growth restriction, pre-eclampsia and pre-term delivery rates were 7.1%, 14.3%, 2.4% and 23.1%, respectively. Cases with uterine artery Doppler abnormalities had significantly poorer obstetric outcomes. Antiphospholipid antibodies, renal involvement and lupus activation did not have any significant influence on poor obstetric outcome. Multidisciplinary approach to the care of pregnant women with SLE is mandatory for good maternal and fetal outcomes. Uterine artery Doppler seems to be a good prognostic factor for adverse obstetric outcomes. |
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Authors:
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R Madazli; B Bulut; H Erenel; A Gezer; O Guralp |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology Volume: 30 ISSN: 1364-6893 ISO Abbreviation: J Obstet Gynaecol Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2010-02-03 Completed Date: 2010-04-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8309140 Medline TA: J Obstet Gynaecol Country: England |
Other Details:
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Languages: eng Pagination: 17-20 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Istanbul University, Istanbul, Turkey. madazli@superonline.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Humans Lupus Erythematosus, Systemic / complications*, diagnosis Pregnancy Pregnancy Complications / diagnosis, etiology* Pregnancy Outcome Retrospective Studies Young Adult |
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