Document Detail


Systemic lupus erythematosus and pregnancy.
MedLine Citation:
PMID:  20121497     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We present a retrospective study of 42 consecutive cases of systemic lupus erythematosus (SLE) and pregnancy followed and delivered during the period 2002-2007 in our department. The mean patient age was 28.6 years and the nulliparity rate was 45.2%. Disease flare up occurred in 9.5% of patients. Lupus anticoagulants, anticardiolipin IgG and IgM antibodies were positive in 33%, 16.6% and 19% of patients, respectively. Mean gestational age at delivery was 36.9 +/- 4.2 and mean birth weight was 2,750 +/- 844 g. Stillbirth, fetal growth restriction, pre-eclampsia and pre-term delivery rates were 7.1%, 14.3%, 2.4% and 23.1%, respectively. Cases with uterine artery Doppler abnormalities had significantly poorer obstetric outcomes. Antiphospholipid antibodies, renal involvement and lupus activation did not have any significant influence on poor obstetric outcome. Multidisciplinary approach to the care of pregnant women with SLE is mandatory for good maternal and fetal outcomes. Uterine artery Doppler seems to be a good prognostic factor for adverse obstetric outcomes.
Authors:
R Madazli; B Bulut; H Erenel; A Gezer; O Guralp
Related Documents :
17211997 - Pregnancy-associated recurrent liver necrosis in patient with antiphospholipid syndrome.
19584727 - Prevention of complete heart block in children of mothers with anti-ssa/ro and anti-ssb...
20688887 - A systematic review and meta-analysis of pregnancy outcomes in patients with systemic l...
24791967 - Does endometrial injury improve implantation of frozen-thawed embryos?
18476167 - Endocrine-immune interactions in pregnant non-human primates with intrauterine infection.
11499067 - Future directions.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology     Volume:  30     ISSN:  1364-6893     ISO Abbreviation:  J Obstet Gynaecol     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-02-03     Completed Date:  2010-04-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309140     Medline TA:  J Obstet Gynaecol     Country:  England    
Other Details:
Languages:  eng     Pagination:  17-20     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Istanbul University, Istanbul, Turkey. madazli@superonline.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Female
Humans
Lupus Erythematosus, Systemic / complications*,  diagnosis
Pregnancy
Pregnancy Complications / diagnosis,  etiology*
Pregnancy Outcome
Retrospective Studies
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Labour outcome of women with successful external cephalic version: A prospective study.
Next Document:  The association between leisure time physical activity in the year before pregnancy and pre-eclampsi...