Document Detail


Systemic lupus erythematosus in a patient with remitting minimal change nephrotic syndrome.
MedLine Citation:
PMID:  9403219     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Minimal change nephrotic syndrome (MCNS) developed in a 17-year-old female and spontaneously remitted. One month later the nephrotic syndrome relapsed. Prednisolone therapy, 60 mg/day, was started and resulted in a full remission within a week and the prednisolone dose was subsequently tapered. Seven months later, when 10 mg/day of prednisolone was being administered, she developed erythematous rash with photosensitivity and polyarthralgia without exacerbation of the nephrotic syndrome, and fulfilled four of the American College of Rheumatology criteria for classification of systemic lupus erythematosus (SLE). Avoidance of direct sunlight ameliorated the erythematous rash and the polyarthralgia disappeared even though the prednisolone dose was decreased further. This is the first reported case of SLE developed in a patient with remitting MCNS.
Authors:
G Nishihara; M Nakamoto; C Yasunaga; K Takeda; K Matsuo; M Urabe; T Goya; T Sakemi
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Clinical nephrology     Volume:  48     ISSN:  0301-0430     ISO Abbreviation:  Clin. Nephrol.     Publication Date:  1997 Nov 
Date Detail:
Created Date:  1998-01-30     Completed Date:  1998-01-30     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0364441     Medline TA:  Clin Nephrol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  327-30     Citation Subset:  IM    
Affiliation:
Kidney Center, Saiseikai Yahata Hospital, Kitakyushu, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Biopsy
Female
Humans
Kidney / pathology,  ultrastructure
Lupus Erythematosus, Systemic / complications*,  drug therapy,  pathology
Nephrosis, Lipoid / complications*,  drug therapy,  pathology
Prednisolone / therapeutic use
Recurrence
Remission, Spontaneous
Chemical
Reg. No./Substance:
50-24-8/Prednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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