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Systemic lupus erythematosus complicated with posterior reversible encephalopathy syndrome and intracranial vasculopathy.
MedLine Citation:
PMID:  21199460     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Posterior reversible encephalopathy syndrome (PRES) is a neurotoxic condition characterized by reversible vasogenic edema on neuroimaging. It is associated with various neurological manifestations, including headaches, vomiting, seizures, visual loss, altered mental status and focal neurological deficits. PRES mainly occurs in the setting of eclampsia, hypertension, uremia, malignancy, transplantation, autoimmune diseases and/or use of immunosuppressive drugs. This syndrome has been described in patients with systemic lupus erythematosus (SLE). PRES is a potentially reversible clinical-radiological entity; however, it can be complicated with vasculopathy, infarction or hemorrhage. Vasculopathy has been demonstrated to be a common finding in patients with SLE. We report the case of a woman with lupus nephritis and PRES whose diffuse vasculopathy was present on initial neuroimaging. Subsequent brain computed tomography scan demonstrated interval development of intraparenchymal hemorrhage and subarachnoid hemorrhage. To our knowledge, this unique brain image pattern has not been reported in SLE patients.
Authors:
Hung-An Chen; Yeong-Jang Lin; Pei-Chih Chen; Tai-Yuan Chen; Kao-Chang Lin; He-Hsiung Cheng
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of rheumatic diseases     Volume:  13     ISSN:  1756-185X     ISO Abbreviation:  Int J Rheum Dis     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2011-01-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101474930     Medline TA:  Int J Rheum Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  e79-82     Citation Subset:  IM    
Copyright Information:
© 2010 Asia Pacific League of Associations for Rheumatology and Blackwell Publishing Asia Pty Ltd.
Affiliation:
Divisions of Allergy-Immunology-Rheumatology Diagnostic Radiology Neurology, Chi Mei Medical Center, Tainan Division of Allergy-Immunology-Rheumatology, Chang Bing Show Chwan Memorial Hospital, Lu-Gang, Taiwan.
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