| Systemic lactose intolerance: a new perspective on an old problem. | |
| | |
MedLine Citation:
|
PMID: 15749792 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Intolerance to certain foods can cause a range of gut and systemic symptoms. The possibility that these can be caused by lactose has been missed because of "hidden" lactose added to many foods and drinks inadequately labelled, confusing diagnosis based on dietary removal of dairy foods. Two polymorphisms, C/T13910 and G/A22018, linked to hypolactasia, correlate with breath hydrogen and symptoms after lactose. This, with a 48 hour record of gut and systemic symptoms and a six hour breath hydrogen test, provides a new approach to the clinical management of lactose intolerance. The key is the prolonged effect of dietary removal of lactose. Patients diagnosed as lactose intolerant must be advised of "risk" foods, inadequately labelled, including processed meats, bread, cake mixes, soft drinks, and lagers. This review highlights the wide range of systemic symptoms caused by lactose intolerance. This has important implications for the management of irritable bowel syndrome, and for doctors of many specialties. |
| | |
Authors:
|
S B Matthews; J P Waud; A G Roberts; A K Campbell |
Publication Detail:
|
Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
|
Title: Postgraduate medical journal Volume: 81 ISSN: 1469-0756 ISO Abbreviation: Postgrad Med J Publication Date: 2005 Mar |
Date Detail:
|
Created Date: 2005-03-07 Completed Date: 2005-06-16 Revised Date: 2010-09-21 |
Medline Journal Info:
|
Nlm Unique ID: 0234135 Medline TA: Postgrad Med J Country: England |
Other Details:
|
Languages: eng Pagination: 167-73 Citation Subset: IM |
Affiliation:
|
Department of Medical Biochemistry and Immunology, Llandough Hospital, Cardiff and Vale NHS Trust, Penarth Vale of Glamorgan, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Asthma
/
etiology Breath Tests / methods Eczema / etiology Female Humans Irritable Bowel Syndrome / etiology Lactase / deficiency Lactose Intolerance / complications, diagnosis*, diet therapy Lactose Tolerance Test / methods Middle Aged Osteoarthritis / etiology |
| Chemical | |
Reg. No./Substance:
|
EC 3.2.1.108/Lactase |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Drunken patients in the general hospital: their care and management.
Next Document: Adult intussusception: case reports and review of literature.