Document Detail


Systemic high-sensitivity C-reactive protein levels in normal-tension glaucoma and primary open-angle glaucoma.
MedLine Citation:
PMID:  17438427     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To determine the systemic high-sensitivity C-reactive protein (hsCRP) level in patients with normal tension glaucoma (NTG) and primary open-angle glaucoma (POAG). MATERIALS AND METHODS: With the exclusion of patients with cardiovascular and other systemic diseases, 40 patients with NTG, 40 with POAG, and 40 normal controls were enrolled in this study. Each patient underwent blood sampling for hsCRP, biochemistry, and lipid profile analysis. RESULTS: Each group had similar demographic parameters including the age, sex, body mass index, heart rate, and blood pressure. There was no statistically significant difference in the hsCRP and biochemistry results between the 3 groups. The lipid profile exhibited a mild elevation in the patients with POAG. CONCLUSIONS: Our data revealed no difference in the hsCRP level between NTG, POAG, and normal controls after exclusion of patients with cardiovascular and other systemic diseases. Systemic vascular inflammation may not be a major cause in the pathogenesis of glaucoma in those without histories of cardiovascular diseases.
Authors:
Wei-Wen Su; Wan-Jing Ho; Shih-Tsung Cheng; Shirley H L Chang; Shiu-Chen Wu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of glaucoma     Volume:  16     ISSN:  1057-0829     ISO Abbreviation:  J. Glaucoma     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-04-17     Completed Date:  2007-05-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9300903     Medline TA:  J Glaucoma     Country:  United States    
Other Details:
Languages:  eng     Pagination:  320-3     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Tao-Yuan, Taiwan.
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MeSH Terms
Descriptor/Qualifier:
Blood Pressure
Body Mass Index
C-Reactive Protein / analysis*
Female
Glaucoma, Open-Angle / blood*
Heart Rate
Humans
Intraocular Pressure
Lipids / blood
Male
Middle Aged
Ocular Hypertension / blood
Chemical
Reg. No./Substance:
0/Lipids; 9007-41-4/C-Reactive Protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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