| Systemic hantavirus-infection in a comatose HIV patient. | |
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MedLine Citation:
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PMID: 23341221 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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SYMPTOMS: A 40 year old, disoriented, HIV- and Hepatitis B positive male patient was admitted with 40.3 °C. Clinically he presented a sinustachycardia (160/min) and hypotension (70/60 mmHg). INVESTIGATIONS/DIAGNOSIS: Laboratory analyses showed elevated infection parameters, azotemia, proteinuria and thrombopenia. CD(4+)T-helper cells: 320/µl (32 %), HIV RNA: < 40 copies/ml, Hepatitis B DNA: 20800 copies/ml. Hantavirus serology (immunofluorescence antibody assay): 1:2048; serotype Puumala. TREATMENT/COURSE: An early-goal-directed therapy and antibiotic treatment with Piperacillin and Tazobactam was initiated. The patient developed a bipulmonal infiltrate and an acute respiratory distress syndrome (ARDS ) requiring tracheal intubation, as well as a triad of fever, renal failure and profound hemorrhagic symptoms. This led to the diagnosis of the Puumala infection. Due to the parallel HIV- and Hepatits B infection an antiretroviral therapy was initiated. CONCLUSION: In summary the Puumala infection bears the potential for a severe multi-organ failure, which is not typical for this usually benign infection. |
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Authors:
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Robert Larbig; Clara Lehman; Dennis Rottländer; Sara Reda; Guido Michels; Uta C Hoppe; Mathias Kochanek |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-23 |
Journal Detail:
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Title: Wiener medizinische Wochenschrift (1946) Volume: - ISSN: 1563-258X ISO Abbreviation: Wien Med Wochenschr Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-1-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8708475 Medline TA: Wien Med Wochenschr Country: - |
Other Details:
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Languages: GER Pagination: - Citation Subset: - |
Affiliation:
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Universitätsklinik II für Innere Medizin, Paracelsus Medizinische Universität Salzburg, Müllner Hauptstrasse 48, 5020, Salzburg, Österreich, r.larbig@salk.at. |
Vernacular Title:
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Systemische Hantavirus-Infektion bei einem komatösen HIV Patienten. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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