Document Detail


Systemic giant cell arteritis and cerebellar infarction.
MedLine Citation:
PMID:  8506563     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND PURPOSE: Systemic giant cell arteritis causing cerebellar infarction due to intracranial arteritis of the anterior inferior cerebellar artery has not been previously reported. We report this infrequent occurrence and discuss the differential diagnosis. CASE DESCRIPTION: An 85-year-old woman was admitted with a 2-week history of episodic ataxia, unilateral headaches, and vomiting. She had a history of atrial fibrillation and breast carcinoma. Her mental state was initially normal, and there were right-sided cerebellar signs. An ejection systolic murmur was heard, and peripheral pulses were palpable. A postmortem examination revealed cerebellar infarction due to giant cell arteritis of the anterior inferior cerebellar artery and basilar arteries. Systemic giant cell arteritis was also present. CONCLUSIONS: Giant cell arteritis is a systemic disorder that can infrequently involve intracranial vessels, including the basilar, vertebral, and anterior cerebellar arteries. Cerebellar infarction secondary to the arteritis may occur. The distribution and size of intracranial vessel involvement is distinct from isolated cranial angiitis.
Authors:
C A Mclean; M F Gonzales; J P Dowling
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Stroke; a journal of cerebral circulation     Volume:  24     ISSN:  0039-2499     ISO Abbreviation:  Stroke     Publication Date:  1993 Jun 
Date Detail:
Created Date:  1993-07-07     Completed Date:  1993-07-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0235266     Medline TA:  Stroke     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  899-902     Citation Subset:  IM    
Affiliation:
Department of Anatomical Pathology, Royal Melbourne Hospital, Victoria, Australia.
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MeSH Terms
Descriptor/Qualifier:
Aged
Arteritis / complications*,  pathology
Basilar Artery / pathology
Cerebellum / blood supply
Cerebral Infarction / etiology*,  pathology
Female
Giant Cells
Heart Murmurs / complications
Humans
Purkinje Cells / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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