Document Detail

Systemic fluorides: drops and tablets.
MedLine Citation:
PMID:  8500133     Owner:  NLM     Status:  MEDLINE    
Fluoride drops and tablets are effective caries-inhibiting agents which exercise their benefit through mainly topical means. Results of caries trials in which drops or tablets were used in the home vary from excellent to poor, depending on the compliance rates of both parents and offspring. Delivery in schools has also produced reductions of > 80%, and as poor as 20%, again possibly dependent on teacher vigilance. The pre-natal controversy re fluoride tablet benefits has only recently been tested under a true double-blind protocol and resulted in a non-significant effect, although the trend was in favour of those whose mothers had taken F- tablets during pregnancy. Hence, while at the individual level, the slow intra-oral dissolution of fluoride tablets can be of great benefit for coronal caries in children, adolescents, and possibly medically compromised adults (with or without root caries), their contribution on a community basis cannot readily be compared with that of water or salt fluoridation. Although fluoride tablets have been held responsible for an increase in fluorosis prevalence, data which were assessed blind now exist to show that a daily dosage of 0.25 mg fluoride from birth is not associated with dental fluorosis, if additional fluoride products are not used injudiciously over the same period.
K W Stephen
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Caries research     Volume:  27 Suppl 1     ISSN:  0008-6568     ISO Abbreviation:  Caries Res.     Publication Date:  1993  
Date Detail:
Created Date:  1993-06-30     Completed Date:  1993-06-30     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0103374     Medline TA:  Caries Res     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  9-15     Citation Subset:  D; IM    
Department of Oral Medicine and Pathology, University of Glasgow Dental School, UK.
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MeSH Terms
Administration, Oral
Child, Preschool
Dental Caries / prevention & control*
Fluorides / administration & dosage*,  adverse effects
Fluorosis, Dental / etiology
Prenatal Care
Root Caries / prevention & control
Reg. No./Substance:
0/Fluorides; 0/Tablets

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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