| Systemic combination treatment for psoriasis: a review. | |
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MedLine Citation:
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PMID: 20574597 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Psoriasis is a chronic inflammatory skin disease, which affects approximately 2.6% of the population in Northern Europe and Scandinavia. In order to achieve disease control, combinations of systemic treatments are sometimes needed for variable time periods. However, no evidence-based guidelines exist for the use of systemic combination therapy. Therefore, our aim was to review the current literature on systemic anti-psoriatic combination regimens. We searched PubMed and identified 98 papers describing 116 studies (23 randomized) reporting on the effect of various systemic combination treatments. The most thoroughly investigated combination was retinoid and phototherapy. Further controlled research is needed to define the safest and most effective combination regimens. |
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Authors:
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Peter Jensen; Lone Skov; Claus Zachariae |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Acta dermato-venereologica Volume: 90 ISSN: 1651-2057 ISO Abbreviation: Acta Derm. Venereol. Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-06-24 Completed Date: 2010-10-12 Revised Date: 2012-01-02 |
Medline Journal Info:
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Nlm Unique ID: 0370310 Medline TA: Acta Derm Venereol Country: Sweden |
Other Details:
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Languages: eng Pagination: 341-9 Citation Subset: IM |
Affiliation:
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Department of Dermato-Allergology, Copenhagen University Hospital Gentofte, Denmark. peterj01@geh.regionh.dk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biological Agents
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therapeutic use Cyclosporine / therapeutic use Dermatologic Agents / therapeutic use* Drug Therapy, Combination Evidence-Based Medicine Humans Methotrexate / therapeutic use Photochemotherapy* Photosensitizing Agents / therapeutic use* Psoriasis / drug therapy* Retinoids / therapeutic use Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Biological Agents; 0/Dermatologic Agents; 0/Photosensitizing Agents; 0/Retinoids; 59-05-2/Methotrexate; 59865-13-3/Cyclosporine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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