Document Detail

Systemic blood pressure and capillary blood-cell velocity in glaucoma patients: a preliminary study.
MedLine Citation:
PMID:  7549448     Owner:  NLM     Status:  MEDLINE    
Systemic hypotension and vasospasm have both been suggested as risk factors for glaucomatous damage. Furthermore, a relationship between the incidence of vasospastic disorders and systemic hypotension has been reported. This preliminary study investigated the relationship between these two risk factors. In 20 glaucoma patients suspected to have vascular risk factors, time of blood-flow standstill was measured under cold provocation in nailfold capillaries and 24-hour blood pressure was monitored. Nine were high-tension glaucoma patients but progressing despite medically well-controlled intraocular pressure, and 11 had normal-tension glaucoma. Thirteen patients were vasospastic, and seven were not. Patients without vasospasm had a significantly lower mean systolic blood pressure during the daytime (113.4 +/- 7.1 mmHg) than vasospastic patients (122.6 +/- 12.8 mmHg), p = 0.026. The time of blood-flow standstill in vasospastic patients, however, correlated with the lowest individual systolic blood pressure reading (r = -0.56; p = 0.049). These low readings occurred mostly during the night ("deepers").
S Orgül; H J Kaiser; J Flammer; P Gasser
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of ophthalmology     Volume:  5     ISSN:  1120-6721     ISO Abbreviation:  Eur J Ophthalmol     Publication Date:    1995 Apr-Jun
Date Detail:
Created Date:  1995-11-07     Completed Date:  1995-11-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9110772     Medline TA:  Eur J Ophthalmol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  88-91     Citation Subset:  IM    
University Eye Clinic, Basel, Switzerland.
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MeSH Terms
Blood Flow Velocity / physiology
Blood Pressure / physiology*
Glaucoma, Open-Angle / physiopathology*
Intraocular Pressure
Middle Aged
Ocular Hypertension / physiopathology*
Pilot Projects
Skin / blood supply

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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