Document Detail


Systemic associations of dynamic retinal vessel analysis: a review of current literature.
MedLine Citation:
PMID:  23151190     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Endothelial dysfunction is a key pathogenic mechanism of cardiovascular diseases. The retinal microvascular network offers a unique, non-invasive window to study endothelial function. Recently, dynamic measurement of retinal vessel caliber using flicker light stimulation has been used to evaluate potential endothelial dysfunction and other mechanisms in cardiovascular diseases. A variety of studies now indicate that retinal vasodilation during flicker light simulation is reduced in diabetes, hypertension, hyperlipidemia and obesity, and may be influenced by age and race/ethnicity. These data suggest flicker light-induced retinal vasodilation may be a unique and non-invasive measure of endothelial dysfunction. This review focuses recent studies on systemic associations of flicker light-induced retinal vasodilation, and discusses the potential for future research in this area. © 2012 John Wiley & Sons Ltd.
Authors:
Michelle Lim; M Bayu Sasongko; M Kamran Ikram; Ecosse Lamoureux; Jie Jin Wang; Tien Yin Wong; Carol Y Cheung
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-15
Journal Detail:
Title:  Microcirculation (New York, N.Y. : 1994)     Volume:  -     ISSN:  1549-8719     ISO Abbreviation:  Microcirculation     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9434935     Medline TA:  Microcirculation     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 John Wiley & Sons Ltd.
Affiliation:
Centre for Eye Research Australia, University of Melbourne, Australia; Singapore Eye Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
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