Document Detail


Systemic amyloidosis with temporal artery involvement mimicking temporal arteritis.
MedLine Citation:
PMID:  9101575     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 77-year-old man presented with jaw claudication, arthralgias and myalgias, weight loss, marked fatigue, and thickened temporal arteries. No vasculitis was seen on the temporal artery biopsy specimen, but amyloidosis was suspected and confirmed with Congo red staining. Subsequent bone marrow biopsy revealed multiple myeloma. Although the patient initially was thought to have temporal arteritis, the results of temporal artery biopsy directed further investigations that led to the diagnosis of systemic amyloidosis. Systemic amyloidosis should be considered in the differential diagnosis when patients, especially men, present with clinical findings suggestive of temporal arteritis but without evidence of vasculitis in temporal artery biopsy specimens.
Authors:
E B Ing; I Z Woolf; B R Younge; J Bjornsson; J A Leavitt
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Ophthalmic surgery and lasers     Volume:  28     ISSN:  1082-3069     ISO Abbreviation:  Ophthalmic Surg Lasers     Publication Date:  1997 Apr 
Date Detail:
Created Date:  1997-06-17     Completed Date:  1997-06-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9517132     Medline TA:  Ophthalmic Surg Lasers     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  328-31     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Mayo Clinic, Rochester, MN 55905, USA.
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MeSH Terms
Descriptor/Qualifier:
Aged
Amyloidosis / complications,  diagnosis*
Arthralgia / complications,  diagnosis
Biopsy
Diagnosis, Differential
Giant Cell Arteritis / complications,  diagnosis*
Humans
Male
Peripheral Vascular Diseases / complications,  diagnosis
Temporal Arteries / pathology*
Vision Disorders / complications,  diagnosis
Visual Acuity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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