Document Detail

Systemic amyloidosis manifesting as localized, severe periodontitis.
MedLine Citation:
PMID:  15202754     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Amyloidosis comprises a heterogenous group of disorders characterized by amyloid deposition in various organs. The authors document a case in which amyloidosis manifested as a localized, severe, periodontal disease. CASE DESCRIPTION: A 73-year-old woman visited her dentist because of pain and increased mobility of her mandibular bridge. Radiographic examination revealed severe vertical bone loss associated with tooth no. 27. One of the authors extracted the tooth, removed tissue with a curet from this site and submitted it for pathological examination. He made a diagnosis of amyloidosis on the basis of histological and immunohistochemical findings. CLINICAL IMPLICATIONS: Clinicians should consider periodontal involvement in amyloidosis as a possible cause of severe, localized, periodontal disease, particularly in patients with chronic inflammatory disorders or a history of amyloidosis.
Samer Khoury; Joseph J Dusek; Gissela B Anderson; Nadarajah Vigneswaran
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the American Dental Association (1939)     Volume:  135     ISSN:  0002-8177     ISO Abbreviation:  J Am Dent Assoc     Publication Date:  2004 May 
Date Detail:
Created Date:  2004-06-18     Completed Date:  2004-08-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7503060     Medline TA:  J Am Dent Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  617-23     Citation Subset:  D; IM    
University of Texas Health Science Center at Houston, Dental Branch, 77030, USA.
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MeSH Terms
Alveolar Bone Loss / etiology,  pathology
Amyloidosis / classification,  complications,  diagnosis*,  pathology
Diagnosis, Differential
Periodontitis / diagnosis*

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