Document Detail

Systemic adverse reactions to prostaglandin F2 (PGF2 alpha, dinoprostone, prostin F2 alpha, prostalmon F).
MedLine Citation:
PMID:  6961113     Owner:  NLM     Status:  MEDLINE    
Prostaglandins are mainly used in clinical medicine for midterm abortion and to terminate pregnancy. Systemic adverse reactions include nausea and vomiting, which occur in approximately half of the patients and, to a lesser extent, diarrhea. Although bronchospasm occurs infrequently, PGF2 should be avoided in asthmatics. Cardiorespiratory failure culminating in prolonged coma and death has been reported. Moreover, convulsions and EEG changes have been observed in a comparatively small number of cases.
L Wislicki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of biological research in pregnancy     Volume:  3     ISSN:  0173-8593     ISO Abbreviation:  Int J Biol Res Pregnancy     Publication Date:  1982  
Date Detail:
Created Date:  1983-03-24     Completed Date:  1983-03-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8011123     Medline TA:  Int J Biol Res Pregnancy     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  158-60     Citation Subset:  IM    
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MeSH Terms
Abortifacient Agents / adverse effects*
Abortion, Induced
Bronchial Spasm / chemically induced
Diarrhea / chemically induced
Heart Arrest / chemically induced
Prostaglandins / adverse effects*
Prostaglandins E / adverse effects
Prostaglandins E, Synthetic / adverse effects
Prostaglandins F / adverse effects
Seizures / chemically induced
Vomiting / chemically induced
Reg. No./Substance:
0/Abortifacient Agents; 0/Prostaglandins; 0/Prostaglandins E; 0/Prostaglandins E, Synthetic; 0/Prostaglandins F; 363-24-6/Dinoprostone; 551-11-1/Dinoprost; 60325-46-4/sulprostone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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