| Systemic Candida infection in University hospital 1997-1999: the distribution of Candida biotypes and antifungal susceptibility patterns. | |
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MedLine Citation:
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PMID: 11307597 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A total of 102 Candida species were isolated from blood cultures from January 1997 to October 1999. Using assimilation of carbohydrate test, 52 (51.0%) of the Candida sp. were identified as C. parapsilosis, 25.5% (26) were C. tropicalis. C. albicans made up 11.8% (12), 6.9% (7) were C. rugosa, 3.8% (4) C. glabrata and 1% (1) C. guilliermondii. No C. dubliniensis was found in the study. In vitro antifungal susceptibility tests showed that all Candida species were sensitive to nystatin, amphotericin B and ketoconazole. Although all isolates remained sensitive to fluconazole, intermediate susceptibility was found in 3 C. rugosa isolates. Antifungal agents with high frequency of resistance were econazole, clotrimazole, miconazole and 5-fluorocytosine. Candida species found to have resistance to these antifungal agents were non-C. albicans. |
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Authors:
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K P Ng; T L Saw; S L Na; T S Soo-Hoo |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Mycopathologia Volume: 149 ISSN: 0301-486X ISO Abbreviation: Mycopathologia Publication Date: 2001 |
Date Detail:
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Created Date: 2001-04-18 Completed Date: 2001-08-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7505689 Medline TA: Mycopathologia Country: Netherlands |
Other Details:
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Languages: eng Pagination: 141-6 Citation Subset: IM |
Affiliation:
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Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. kpng@medicine.med.um.edu.my |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antifungal Agents
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pharmacology* Candida / classification*, drug effects, metabolism Candidiasis / blood, drug therapy, microbiology* Carbohydrate Metabolism Cross Infection / blood, drug therapy, microbiology* Drug Resistance, Microbial Hospitals, University Humans Microbial Sensitivity Tests |
| Chemical | |
Reg. No./Substance:
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0/Antifungal Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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