Document Detail

Systematic screening for active tuberculosis: rationale, definitions and key considerations.
MedLine Citation:
PMID:  23407219     Owner:  NLM     Status:  MEDLINE    
The impact of current interventions to improve early detection of tuberculosis (TB) seems to have been saturated. Case detection trends have stagnated. TB incidence is falling in most settings worldwide, but the rate of decline is far lower than expected. There is growing evidence from national TB prevalence surveys and other research of a large pool of undetected TB in the community. Intensified efforts to further break down access barriers and scale up new and rapid diagnostic tools are likely to improve the situation. However, will these be enough? Or do we also need to reach out more towards people who do not actively seek care with well-recognisable TB symptoms? There have recently been calls to revisit TB screening, particularly in high-risk groups. The World Health Organization (WHO) recommends screening for TB in people with human immunodeficiency virus infection and in close TB contacts. Should other risk groups also be screened systematically? Could mass, community-wide screening, which the WHO has discouraged over the past four decades, be of benefit in some situations? If so, what screening tools and approaches should be used? The WHO is in the process of seeking answers to these questions and developing guidelines on systematic screening for active TB. In this article, we present the rationale, definitions and key considerations underpinning this process.
K Lönnroth; E Corbett; J Golub; P Godfrey-Faussett; M Uplekar; D Weil; M Raviglione
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease     Volume:  17     ISSN:  1815-7920     ISO Abbreviation:  Int. J. Tuberc. Lung Dis.     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-14     Completed Date:  2013-07-26     Revised Date:  2014-05-05    
Medline Journal Info:
Nlm Unique ID:  9706389     Medline TA:  Int J Tuberc Lung Dis     Country:  France    
Other Details:
Languages:  eng     Pagination:  289-98     Citation Subset:  IM    
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MeSH Terms
Contact Tracing
Early Diagnosis
HIV Infections / epidemiology
Health Priorities
Health Services Needs and Demand
Mass Screening* / methods,  standards
Patient Selection
Practice Guidelines as Topic
Predictive Value of Tests
Risk Assessment
Risk Factors
Tuberculosis / diagnosis*,  epidemiology
Grant Support
091769//Wellcome Trust

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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