Document Detail

Systematic review: transient left ventricular apical ballooning: a syndrome that mimics ST-segment elevation myocardial infarction.
MedLine Citation:
PMID:  15583228     Owner:  NLM     Status:  MEDLINE    
The transient left ventricular apical ballooning syndrome, also known as takotsubo cardiomyopathy, is characterized by transient wall-motion abnormalities involving the left ventricular apex and mid-ventricle in the absence of obstructive epicardial coronary disease. In this paper, we review case series that report on patients with the transient left ventricular apical ballooning syndrome to better characterize patients presenting with the syndrome. We identified 7 case series that reported on at least 5 consecutive patients with the transient left ventricular apical ballooning syndrome. The syndrome more often affects postmenopausal women (82% to 100%) (mean age, 62 to 75 years). Patients commonly present with ST-segment elevation in the precordial leads, chest pain, relatively minor elevation of cardiac enzyme and biomarker levels, and transient apical systolic left ventricular dysfunction despite the absence of obstructive epicardial coronary disease. An episode of emotional or physiologic stress frequently precedes presentation with the syndrome. The in-hospital mortality rate seems to be low, as does the risk for recurrence.
Kevin A Bybee; Tomas Kara; Abhiram Prasad; Amir Lerman; Greg W Barsness; R Scott Wright; Charanjit S Rihal
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Annals of internal medicine     Volume:  141     ISSN:  1539-3704     ISO Abbreviation:  Ann. Intern. Med.     Publication Date:  2004 Dec 
Date Detail:
Created Date:  2004-12-07     Completed Date:  2004-12-21     Revised Date:  2005-04-22    
Medline Journal Info:
Nlm Unique ID:  0372351     Medline TA:  Ann Intern Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  858-65     Citation Subset:  AIM; IM    
Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
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MeSH Terms
Cardiomyopathies / diagnosis*,  physiopathology
Diagnosis, Differential
Myocardial Infarction / diagnosis*,  physiopathology
Sex Factors
Ventricular Dysfunction, Left / diagnosis*,  physiopathology
Comment In:
Ann Intern Med. 2005 Apr 19;142(8):678; author reply 678-9   [PMID:  15838082 ]
Ann Intern Med. 2005 Apr 19;142(8):677-8; author reply 678-9   [PMID:  15838080 ]
Ann Intern Med. 2005 Apr 19;142(8):678; author reply 678-9   [PMID:  15838081 ]

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