Document Detail


Systematic review and meta-analysis methodology.
MedLine Citation:
PMID:  20656933     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Systematic reviews and meta-analyses are being increasingly used to summarize medical literature and identify areas in which research is needed. Systematic reviews limit bias with the use of a reproducible scientific process to search the literature and evaluate the quality of the individual studies. If possible the results are statistically combined into a meta-analysis in which the data are weighted and pooled to produce an estimate of effect. This article aims to provide the reader with a practical overview of systematic review and meta-analysis methodology, with a focus on the process of performing a review and the related issues at each step.
Authors:
Mark Crowther; Wendy Lim; Mark A Crowther
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-07-23
Journal Detail:
Title:  Blood     Volume:  116     ISSN:  1528-0020     ISO Abbreviation:  Blood     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-10-29     Completed Date:  2010-12-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7603509     Medline TA:  Blood     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3140-6     Citation Subset:  AIM; IM    
Affiliation:
Department of Haematology, Worcestershire Royal Hospital, Worcester, United Kingdom. crowthrm@mcmaster.ca
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MeSH Terms
Descriptor/Qualifier:
Biomedical Research*
Clinical Trials as Topic
Humans
Meta-Analysis as Topic*
Randomized Controlled Trials as Topic
Review Literature as Topic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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