Document Detail

Systematic review of laparoscopic versus open surgery for colorectal cancer.
MedLine Citation:
PMID:  16845692     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: This study compares the efficacy and safety of laparoscopic surgery (LS) and open surgery (OS) for colorectal cancer. METHODS: An electronic search of the literature was undertaken to identify primary studies and systematic reviews. Information on the efficacy and safety of LS versus OS was analysed. A meta-analysis was conducted to examine long-term outcomes. RESULTS: A systematic review published in 2000 and 12 more recent randomized clinical trials were identified. Compared with OS, LS reduced blood loss and pain, and resulted in a faster return of bowel function and earlier resumption of normal diet. Hospital stay was up to 2 days shorter after LS. No significant differences between the techniques were noted in the incidence of complications or postoperative mortality. The time required to complete LS was significantly longer (0.5-1.0 h more). No significant differences were found between the two procedures in terms of overall mortality, cancer-related mortality or disease recurrence. CONCLUSION: LS takes longer than OS but offers several short-term benefits. However, complication rates are similar for both procedures and no differences were found in long-term outcomes.
M M Reza; J A Blasco; E Andradas; R Cantero; J Mayol
Publication Detail:
Type:  Journal Article; Meta-Analysis; Review    
Journal Detail:
Title:  The British journal of surgery     Volume:  93     ISSN:  0007-1323     ISO Abbreviation:  Br J Surg     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-08-24     Completed Date:  2006-09-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  921-8     Citation Subset:  AIM; IM    
Unidad de Evaluación de Tecnologías Sanitarias, Agencia Laín Entralgo, Consejería de Sanidad y Consumo, Madrid, Spain.
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MeSH Terms
Colectomy / adverse effects,  methods*
Colorectal Neoplasms / surgery*
Laparoscopy / adverse effects,  methods*
Length of Stay
Postoperative Complications / etiology
Randomized Controlled Trials as Topic
Treatment Outcome
Comment In:
Br J Surg. 2007 Feb;94(2):250; author reply 250   [PMID:  17256818 ]
Br J Surg. 2006 Nov;93(11):1434-5   [PMID:  17058300 ]

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