| Systematic review of laparoscopic versus open surgery for colorectal cancer. | |
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MedLine Citation:
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PMID: 16845692 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: This study compares the efficacy and safety of laparoscopic surgery (LS) and open surgery (OS) for colorectal cancer. METHODS: An electronic search of the literature was undertaken to identify primary studies and systematic reviews. Information on the efficacy and safety of LS versus OS was analysed. A meta-analysis was conducted to examine long-term outcomes. RESULTS: A systematic review published in 2000 and 12 more recent randomized clinical trials were identified. Compared with OS, LS reduced blood loss and pain, and resulted in a faster return of bowel function and earlier resumption of normal diet. Hospital stay was up to 2 days shorter after LS. No significant differences between the techniques were noted in the incidence of complications or postoperative mortality. The time required to complete LS was significantly longer (0.5-1.0 h more). No significant differences were found between the two procedures in terms of overall mortality, cancer-related mortality or disease recurrence. CONCLUSION: LS takes longer than OS but offers several short-term benefits. However, complication rates are similar for both procedures and no differences were found in long-term outcomes. |
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Authors:
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M M Reza; J A Blasco; E Andradas; R Cantero; J Mayol |
Publication Detail:
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Type: Journal Article; Meta-Analysis; Review |
Journal Detail:
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Title: The British journal of surgery Volume: 93 ISSN: 0007-1323 ISO Abbreviation: Br J Surg Publication Date: 2006 Aug |
Date Detail:
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Created Date: 2006-08-24 Completed Date: 2006-09-11 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372553 Medline TA: Br J Surg Country: England |
Other Details:
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Languages: eng Pagination: 921-8 Citation Subset: AIM; IM |
Affiliation:
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Unidad de Evaluación de Tecnologías Sanitarias, Agencia Laín Entralgo, Consejería de Sanidad y Consumo, Madrid, Spain. mercedes.reza@salud.madrid.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Colectomy
/
adverse effects,
methods* Colorectal Neoplasms / surgery* Humans Laparoscopy / adverse effects, methods* Length of Stay Postoperative Complications / etiology Randomized Controlled Trials as Topic Treatment Outcome |
| Comments/Corrections | |
Comment In:
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Br J Surg. 2007 Feb;94(2):250; author reply 250
[PMID:
17256818
]
Br J Surg. 2006 Nov;93(11):1434-5 [PMID: 17058300 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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