Document Detail


Systematic review of computer-navigated total knee arthroplasty.
MedLine Citation:
PMID:  22984894     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Conventional total knee arthroplasty (TKA) and the more recently available computer-navigated total knee arthroplasty (CNTKA) use alternative methods to achieve correct limb alignment. This systematic review was undertaken to assess the safety and effectiveness of CNTKA compared with conventional TKA. METHODS: A systematic search of multiple databases identified relevant randomized controlled trials published to August 2012. Study inclusion was established through application of a predetermined protocol, with independent assessment by two reviewers. RESULTS: Thirty randomized controlled trials were included. The majority of adverse events associated with CNTKA were minor and comparable with those seen with conventional TKA. Conversion to conventional TKA was required in 1% of patients undergoing CNTKA. Thirteen trials reporting on satisfactory post-operative radiological alignment of the mechanical axis in the frontal plane were suitable for meta-analysis, which showed a significant total odds ratio (non-event) of 2.32 (95% confidence interval: 1.77-3.04) in favour of CNTKA (P < 0.00001). Clinical outcomes were comparable between the two techniques, with longer-term follow-up suggesting that CNTKA provided no benefit over conventional TKA in terms of sustained functional improvements. CONCLUSIONS: At present, it is unclear whether the significant improvements shown in radiological outcomes after CNTKA translate to measurable clinical benefits. Although an assumption could be made that an improvement in post-operative alignment should lead to an improvement in patient-related outcomes, the available literature did not clearly show this. Further, long-term trials are required to address this issue.
Authors:
Luis A Zamora; Karen J Humphreys; Amber M Watt; Deanne Forel; Alun L Cameron
Related Documents :
24009294 - Long-term effects of addition of mineralocorticoid receptor antagonist to angiotensin i...
21515504 - Outcomes after carotid angioplasty and stenting in symptomatic octogenarians.
2901304 - How reliable is esr as a measure of disease activity in rheumatoid arthritis treated wi...
17035274 - Adalimumab in the therapy of uveitis in childhood.
22687774 - Adrenaline toxicity following accidental administration of the 1:1000 solution during d...
15692524 - The cooperative outcomes group for ent: a multicenter prospective cohort study on the o...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-18
Journal Detail:
Title:  ANZ journal of surgery     Volume:  -     ISSN:  1445-2197     ISO Abbreviation:  ANZ J Surg     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101086634     Medline TA:  ANZ J Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 The Authors. ANZ Journal of Surgery © 2012 Royal Australasian College of Surgeons.
Affiliation:
Australian Safety and Efficacy Register of New Interventional Procedures - Surgical (ASERNIP-S), Royal Australasian College of Surgeons, Adelaide, South Australia, Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  A gluten-free diet effectively reduces symptoms and health care consumption in a Swedish celiac dise...
Next Document:  Seasonal and vertical distribution of putative ammonia-oxidizing thaumarchaeotal communities in an o...