Document Detail


Systematic Review of the Risk of Parkinson's Disease After Mild Traumatic Brain Injury: Results of the International Collaboration on Mild Traumatic Brain Injury Prognosis.
MedLine Citation:
PMID:  24581909     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: To synthesize the best available evidence on the risk of Parkinson's disease (PD) after mild traumatic brain injury (MTBI).
DATA SOURCES: MEDLINE and other databases were searched (1990-2012) with terms including "craniocerebral trauma" and "parkinsonian disorders." Reference lists of eligible articles and relevant systematic reviews and meta-analyses were also searched.
STUDY SELECTION: Controlled clinical trials, cohort studies, and case-control studies were selected according to predefined criteria. Studies had to have a minimum of 30 concussion cases.
DATA EXTRACTION: Eligible studies were critically appraised using a modification of the Scottish Intercollegiate Guidelines Network criteria. Two reviewers independently reviewed and extracted data from accepted studies into evidence tables.
DATA SYNTHESIS: Evidence was synthesized qualitatively according to modified Scottish Intercollegiate Guidelines Network criteria. Sixty-five studies were eligible and reviewed, and 5 of these with a low risk of bias were accepted as scientifically admissible and form the basis of our findings. Among these admissible studies, the definitions of MTBI were highly heterogeneous. One study found a significant positive association between MTBI and PD (odds ratio, 1.5; 95% confidence interval, 1.4-1.7). The estimated odds ratio decreased with increasing latency between MTBI and PD diagnosis, which suggests reverse causality. The other 4 studies did not find a significant association.
CONCLUSIONS: The best available evidence argues against an important causal association between MTBI and PD. There are few high-quality studies on this topic. Prospective studies of long duration would address the limitations of recall of head injury and the possibility of reverse causation.
Authors:
Connie Marras; Cesar A Hincapié; Vicki L Kristman; Carol Cancelliere; Sophie Soklaridis; Alvin Li; Jörgen Borg; Jean-Luc Af Geijerstam; J David Cassidy
Related Documents :
9046739 - A case of congenital ectopic nails on bilateral little fingers.
2797839 - Congenital malformation among newborns at dr. pirngadi hospital medan during 1981-1984.
25348169 - Looking forward, looking back-10 years in urology.
20177559 - Congenital syphilis: a guide to diagnosis and management.
19627259 - Congenital diaphragmatic hernia: review of the literature in reflection of unresolved d...
8275569 - Ambras syndrome: delineation of a unique hypertrichosis universalis congenita and assoc...
23823119 - Digestive tract symptoms in congenital langerhans cell histiocytosis: a fatal condition...
23771559 - Spondyloarthritis associated with acne conglobata, hidradenitis suppurativa and dissect...
7203459 - Primary pulmonary rhabdomyosarcoma: a case report and review of the literature.
Publication Detail:
Type:  REVIEW    
Journal Detail:
Title:  Archives of physical medicine and rehabilitation     Volume:  95     ISSN:  1532-821X     ISO Abbreviation:  Arch Phys Med Rehabil     Publication Date:  2014 Mar 
Date Detail:
Created Date:  2014-3-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985158R     Medline TA:  Arch Phys Med Rehabil     Country:  -    
Other Details:
Languages:  ENG     Pagination:  S238-S244     Citation Subset:  -    
Copyright Information:
Copyright © 2014 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Systematic Review of Prognosis After Mild Traumatic Brain Injury in the Military: Results of the Int...
Next Document:  Systematic Review of the Risk of Dementia and Chronic Cognitive Impairment After Mild Traumatic Brai...