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Systematic Review of the Management of Ischaemic Colitis.
MedLine Citation:
PMID:  22776101     Owner:  NLM     Status:  Publisher    
Aim:  The study reviewed the literature related to ischaemic colitis (IC) to establish an evidence base for its management and to identify factors predicting severity and mortality). Method:  A systematic review of the English language literature was conducted according to recommendations of the PRISMA statement. MEDLINE, Embase and Cochrane Library databases were searched using the key word search: "IC OR colon ischaemia OR colonic ischaemia OR management IC". IC is often misdiagnosed so only studies where the diagnosis was supported by histopathology in every case were included. Critical appraisal was performed of included studies using predefined quality assessment check lists and narrative data synthesis. Results:  2610 publications were identified. Of these eight retrospective case series and three case controlled studies including 1049 patients were included. Medical management was used in 80.3% patients of whom 6.2% died. Surgery was required in 19.6% of whom 39.3% died. The overall mortality of IC was 12.7%. Lack of rectal bleeding, peritonism and renal dysfunction were commonly quoted predictors of severity however right sided IC appeared to be the most significant predictor of outcome. Conclusion:  Most patients with IC can be managed conservatively. Right sided IC may be the most significant predictor of severity. © 2012 The Authors Colorectal Disease © 2012 The Association of Coloproctology of Great Britain and Ireland.
S O'Neill; S Yalamarthi
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-7
Journal Detail:
Title:  Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland     Volume:  -     ISSN:  1463-1318     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883611     Medline TA:  Colorectal Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 The Authors Colorectal Disease © 2012 The Association of Coloproctology of Great Britain and Ireland.
Department of General and Colorectal Surgery, Queen Margaret Hospital, Dunfermline.
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