Document Detail

A system for recording high fidelity cough sound and airflow characteristics.
MedLine Citation:
PMID:  19876736     Owner:  NLM     Status:  MEDLINE    
Cough is considered an early sign of many respiratory diseases. Recently, there has been increased interest in measuring, analyzing, and characterizing the acoustical properties of a cough. In most cases the main focus of those studies was to distinguish between involuntary coughs and ambient sounds over a specified time period. The objective of this study was to develop a system to measure high fidelity voluntary cough sounds to detect lung diseases. To further augment the analysis capability of the system, a non-invasive flow measurement was also incorporated into the design. One of the main design considerations was to increase the fidelity of the recorded sound characteristics by increasing the signal to noise ratio of cough sounds and to minimize acoustical reflections from the environment. To accomplish this goal, a system was designed with a mouthpiece connected to a cylindrical tube. A microphone was attached near the mouthpiece so that its diaphragm was tangent to the inner surface of the cylinder. A pneumotach at the end of the tube measured the airflow generated by the cough. The system was terminated with an exponential horn to minimize sound reflections. Custom software was developed to read, process, display, record, and analyze cough sound and airflow characteristics. The system was optimized by comparing acoustical reflections and total signal to background noise ratios across different designs. Cough measurements were also collected from volunteer subjects to assess the viability of the system. Results indicate that analysis of cough characteristics has the potential to detect lung disease.
W T Goldsmith; A M Mahmoud; J S Reynolds; W G McKinney; A A Afshari; A A Abaza; D G Frazer
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Publication Detail:
Type:  Journal Article     Date:  2009-10-30
Journal Detail:
Title:  Annals of biomedical engineering     Volume:  38     ISSN:  1573-9686     ISO Abbreviation:  Ann Biomed Eng     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-02-03     Completed Date:  2010-04-22     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  0361512     Medline TA:  Ann Biomed Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  469-77     Citation Subset:  IM    
National Institute for Occupational Safety and Health, Health Effects Laboratory Division, Pathology and Physiology Research Branch, 1095 Willowdale Road, Morgantown, WV 26505, USA.
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MeSH Terms
Auscultation / instrumentation*
Cough / diagnosis*,  physiopathology*
Diagnosis, Computer-Assisted / instrumentation*
Equipment Design
Equipment Failure Analysis
Middle Aged
Reproducibility of Results
Sensitivity and Specificity
Signal Processing, Computer-Assisted / instrumentation*
Sound Spectrography / instrumentation*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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