| Syringomyelia and complex regional pain syndrome as complications of multiple sclerosis. | |
| | |
MedLine Citation:
|
PMID: 10448811 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To describe a patient from Southeast Asia with the optic-spinal phenotype of multiple sclerosis who developed syringomyelia and resultant complex regional pain syndrome (formerly named reflex sympathetic dystrophy). DESIGN: Case report. SETTING: Department of neurology at a tertiary care hospital in the Republic of Singapore. PATIENT: A 53-year-old Chinese woman with a history of optic neuritis developed an episode of left hemiparesis leading to a diagnosis of multiple sclerosis. Serial neuroimaging studies revealed an active demyelinating plaque in the cervical area that later progressed into a syrinx. Over a period of 1 year she also developed signs of sympathetic dysfunction including Horner syndrome of the left eye and complex regional pain syndrome in the left hand. CONCLUSIONS: A case of the optic-spinal phenotype of multiple sclerosis that is commonly observed in Southeast Asia is described. This characteristically tissue-destructive form of multiple sclerosis resulted in syringomyelia complicated by a complex regional pain syndrome. Possible pathogenic mechanisms for these associations are discussed. |
| | |
Authors:
|
A Das; K Puvanendran |
Publication Detail:
|
Type: Case Reports; Comparative Study; Journal Article |
Journal Detail:
|
Title: Archives of neurology Volume: 56 ISSN: 0003-9942 ISO Abbreviation: Arch. Neurol. Publication Date: 1999 Aug |
Date Detail:
|
Created Date: 1999-09-15 Completed Date: 1999-09-15 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0372436 Medline TA: Arch Neurol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1021-4 Citation Subset: AIM; IM |
Affiliation:
|
Department of Neurology, National Neuroscience Institute/Tan Tock Seng Hospital, Singapore. Asha_Das@notes.ttsh.gov.sg |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Cervical Vertebrae
/
pathology Cranial Nerve Diseases / complications, pathology Demyelinating Diseases / pathology Evoked Potentials, Somatosensory Female Humans Magnetic Resonance Imaging Middle Aged Multiple Sclerosis / complications* Neural Conduction / physiology Optic Nerve / pathology* Pain / etiology* Phenotype Reflex Sympathetic Dystrophy / complications* Spinal Cord Diseases / complications, pathology Syndrome Syringomyelia / diagnosis*, etiology* Terminology as Topic |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: An uncommon cause of stroke in young adults.
Next Document: Regulation of limbic motor seizures by GABA and glutamate transmission in nucleus tractus solitarius...