Document Detail

Synthetic human calcitonin in refractory Paget's disease of bone.
MedLine Citation:
PMID:  3111398     Owner:  NLM     Status:  MEDLINE    
Fourteen patients with symptomatic and active Paget's disease of bone who had demonstrated resistance to parenteral synthetic salmon calcitonin, oral disodium etidronate, or both in combination were treated with parenteral synthetic human calcitonin. Eleven patients (79%) demonstrated clinical and chemical improvement for up to five years. Two patients received additional benefit with combined synthetic human calcitonin and etidronate disodium.
R D Altman; B Collins-Yudiskas
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of internal medicine     Volume:  147     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1987 Jul 
Date Detail:
Created Date:  1987-07-29     Completed Date:  1987-07-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1305-8     Citation Subset:  AIM; IM    
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MeSH Terms
Aged, 80 and over
Alkaline Phosphatase / blood
Calcitonin / administration & dosage,  therapeutic use*
Drug Therapy, Combination
Etidronic Acid / administration & dosage
Hormones / administration & dosage,  therapeutic use*
Injections, Subcutaneous
Middle Aged
Osteitis Deformans / drug therapy*
Reg. No./Substance:
0/Hormones; 2809-21-4/Etidronic Acid; 9007-12-9/Calcitonin; EC Phosphatase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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