| Synthetic Studies Towards MPC1001: Preparation of a β-hydroxyl-Tyrosine Derivative. | |
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MedLine Citation:
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PMID: 22287813 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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A procedure for the asymmetric synthesis of a novel β-hydroxy-α-amino acid deriverative to be used in the preparation of the natural product MPC1001 and analogs has been developed. The amino acid was efficiently prepared in six steps via a Mukaiyama aldol reaction via a diphenyloxazinone and 3-bromo-4-methoxybenzaldehyde. |
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Authors:
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Paul T Schuber; Robert M Williams |
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Publication Detail:
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Type: JOURNAL ARTICLE |
Journal Detail:
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Title: Tetrahedron letters Volume: 53 ISSN: 0040-4039 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2984819R Medline TA: Tetrahedron Lett Country: - |
Other Details:
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Languages: ENG Pagination: 380-382 Citation Subset: - |
Affiliation:
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Department of Chemistry, Colorado State University, Fort Collins, CO 80523, USA. |
Export Citation:
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Descriptor/Qualifier:
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| Grant Support | |
ID/Acronym/Agency:
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R01 GM068011-02//NIGMS NIH HHS; R01 GM068011-03//NIGMS NIH HHS; R01 GM068011-04//NIGMS NIH HHS; R01 GM068011-05A1//NIGMS NIH HHS; R01 GM068011-06//NIGMS NIH HHS; R01 GM068011-07//NIGMS NIH HHS; R01 GM068011-08//NIGMS NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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